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ProteomicsImpact of glycan positioning on HIV-1 Env glycan shield density, function, and antibody recognition
N-glycans, which represent >50% mass of the HIV-1 envelope (Env) trimer, play important roles for virus-cell entry and immune evasion. How each glycan unit interacts to shape the Env protein-sugar complex and affects Env function is not well understood. Here, high-resolution glycomics analysis of ...
ORGANISM(S): HIV-1 M:G_PT919 
2021-09-09 | PXD017941 | Pride
Glycosylation Env Hiv N262 Gp120 
ProteomicsSerum proteomic analysis of circulating IgA1-containing immune complexes in patients with IgA nephropathy
IgA nephropathy (IgAN) is an autoimmune disease that involves galactose-deficient IgA1 (Gal-deficient IgA1) recognized by autoantibodies to form circulating immune complexes (IgA1-IC). Some of these complexes deposit in the glomeruli and induce kidney injury. Gal-deficient IgA1 alone is not sufficie...
ORGANISM(S): Homo sapiens (Human) 
2025-11-03 | PXD055562 | Pride
Proteomics Lc-ms Complement Orbitrap Raw Immune complexes Serum Iga nephropathy Glomerular disease 
UnknownDefining HIV-1 Envelope N-Glycan Microdomains through Site-Specific Heterogeneity Profiles.
Not available
S-EPMC6288332 | biostudies-literature
MetabolomicsToxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adducts
Toxicometabolomics, essentially applying metabolomics to toxicology of endogenous compounds such as drugs of abuse or new psychoactive substances (NPS), can be investigated by using different in vitro models and dedicated metabolomics techniques to enhance the number of relevant findings. The presen...
2023-10-10 | MTBLS1481 | MetaboLights
UnknownGlycan Positioning Impacts HIV-1 Env Glycan-Shield Density, Function, and Recognition by Antibodies.
Not available
S-EPMC7649354 | biostudies-literature
UnknownSoluble prefusion-closed HIV-envelope trimers with glycan-covered bases.
Not available
S-EPMC10404741 | biostudies-literature
UnknownLongitudinal Changes in Health-Related Quality of Life in Primary Glomerular Disease: Results From the CureGN Study.
Not available
S-EPMC7569685 | biostudies-literature
UnknownDefining subgroups of pediatric nephrotic patients with urine proteomics.
Not available
S-EPMC12393002 | biostudies-literature
UnknownRacial and Ethnic Disparities in Acute Care Utilization Among Patients With Glomerular Disease.
Not available
S-EPMC9974571 | biostudies-literature
UnknownClinical Characteristics and Treatment Patterns of Children and Adults With IgA Nephropathy or IgA Vasculitis: Findings From the CureGN Study.
Not available
S-EPMC6224619 | biostudies-literature
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