Resident tissue macrophages

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Unknown (1082)
Genomics (672)
Transcriptomics (545)
Proteomics (29)
Other (25)
Metabolomics (2)
Methylation profiling (1)

Organisms

Mus musculus (508)
Homo sapiens (120)
Andropogon gerardi (18)
Bacteria (18)
Canis lupus familiaris (18)
Cnidaria (18)
Ensifer adhaerens (18)
Eukaryota (18)
Fasciola (18)
Hepatitis B virus (18)
Human alphaherpesvirus 1 strain 17 (18)
Human alphaherpesvirus 1 strain KOS (18)
Human betaherpesvirus 5 (18)
Human herpesvirus 2 strain 186 (18)
Madurella mycetomatis (18)
Mesocricetus auratus (18)
Miscanthus x giganteus (18)
Mus musculus (18)
Orthoflavivirus (18)
Panicum virgatum (18)
Platyhelminthes (18)
Pseudomonas aeruginosa AES-1R (18)
Rattus norvegicus (18)
Rattus rattus (18)
Rattus norvegicus (11)
Macaca mulatta (5)
Danio rerio (4)
Ovis aries (2)
Sus scrofa (2)
Macaca fascicularis (1)

Organisms

Mus musculus (430)
Homo sapiens (92)
Rattus norvegicus (7)
Macaca mulatta (4)
Danio rerio (4)
Macaca fascicularis (1)
Mus musculus musculus (1)
Sus scrofa (1)

Repository

ENA (609)
geo (523)
biostudies-arrayexpress (110)
pride (18)
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jPOST (3)
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EGA (1)

Tissue

Macrophage (9)
Lung (3)
Cell culture (2)
Heart (2)
Liver (2)
Primary cell (2)
Bone marrow (1)
Brain (1)
Conidium (1)
Milk (1)
Peritoneal macrophage (1)
Peritoneum (1)
Placenta (1)
Spleen (1)
Subcutaneous adipose tissue (1)
White fat cell (1)

Disease

HIV-associated dementia (1)
SS2-infected (1)
COVID-19 (1)
Liver disease (1)
Pneumonia (1)
Severe acute respiratory syndrome coronavirus 2 (1)

Technology Type

Mass Spectrometry (18)
Shotgun proteomics (7)
Bottom-up proteomics (5)
Data-independent acquisition (5)
Mass spectrometry (2)
Data-dependent acquisition (2)
SRM/MRM (1)
SWATH MS (1)

Instrument Platform

Illumina NovaSeq 6000 (9)
Illumina HiSeq 4000 (5)
NextSeq 500 (3)
NextSeq 2000 (2)
Illumina HiSeq 2500 (2)
Q Exactive Plus (2)
R software (1)
Nf-core pipeline (1)
Illumina DNA Tagmentation (1)
Arcturus PicoPure (1)
Miltenyi Biotec (cat no. 130-096-730) ,Fortessa X-20 flow cytometer (BD Biosciences) (1)
QIAGEN (1)
Infinite M Nano, TECAN, Switzerland (1)
Tizol reagent, Sigma-Aldrich (1)
10x Genomics Chromium (1)
BD FACS Aria SORP (1)
Cell Sorter Aria III or Influx (BD biosciences) (1)
The Agilent C scanner (1)
Agilent 2100 Bioanalyzer (1)
Illumina Genome Analyzer (1)
Illumina HiSeq 1500 (1)
NextSeq 550 (1)
6410 Triple Quadrupole LC/MS (1)
6545 Q-TOF LC/MS (1)
Orbitrap Fusion Lumos (1)
Liquid Chromatography MS - positive - reverse-phase (1)
Liquid Chromatography MS - negative - reverse-phase (1)
Liquid Chromatography MS - positive - reverse phase (1)
Liquid Chromatography MS - negative - reverse phase (1)

Publication Date

2026 (85)
2025 (83)
2024 (78)
2023 (67)
2020 (48)
2022 (47)
2021 (37)
2014 (36)
2016 (33)
2019 (32)
2018 (30)
2017 (28)
2015 (20)
2013 (8)
2012 (6)
2008 (6)
2010 (5)
2007 (5)
2009 (3)
2011 (2)
2005 (1)
2004 (1)

Metabolite Name

Adefovir Dipivoxil (Preveon, Hepsera) (1)
Indomethacin (Indocid, Indocin) (1)
MLS001148580-01!6ALPHA,9ALPHA-DIFLUOROPREDNISOLONE 21-ACETATE 17-BUTYRATE (1)
Toremifene Citrate (Fareston, Acapodene) (1)
[(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate (1)
(+)-Cycloolivil 4'-O-¦Â-D-glucopyranoside (1)
(+)-Fasciculic acid B (1)
(+)-Lyoniresinol 2¦Á-O-¦Â-D-glucopyranoside (1)
(-)-Medicocarpin;Medicarpin 3-O-glucoside (1)
(-)-Syringaresinol-4-O-¦Â-D-glucopyranoside (1)
(-)-threo-Iso(homo)2-citrate;(-)-threo-1-Hydroxy-1,2,5-pentanetricarboxylic acid;1-Hydroxypentane-1,2,5-tricarboxylate;threo-(Homo)2-isocitrate (1)
(1)Benzopyrano(5,4,3-cde)(1,3)dioxolo(4,5-h)(1)benzopyran-5,11-dione, 1,2,3-trimethoxy- (1)
(1,3-Dihydroxy-6,8a-dimethyl-3-propan-2-yl-1,2,3a,4,5,8-hexahydroazulen-4-yl) 3,4-dimethoxybenzoate (1)
(10-Hydroxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl) (Z)-2-methylbut-2-enoate (1)
(11E)-11-Octadecenoic acid (1R,2S)-2-[[(Z)-9-hexadecenoyl]oxy]-1-methylpropyl ester (1)
(12Z)-9,10,11,14,15,16,17,18,19,20,21,22-Dodecahydro-5,8-ethenobenzo[20]annulene-2,4,6,24-tetrol (1)
(13S)-13-Ethoxy-1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridine (1)
(14E)-11-hydroxy-14-(1H-imidazol-5-ylmethylidene)-2-methoxy-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.01,13.03,8]hexadeca-3,5,7-triene-12,15-dione (1)
(14S)-9,20,21,25-Tetramethoxy-15-methyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-1(30),3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,28,31-tetradecaen-2-one (1)
(19E,21E,23E,25E,27E,29E,31E)-17-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-1,3,5,33,37-pentahydroxy-18,36-dimethyl-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-9,13,15-trione (1)
(19E,21E,23E,25E,27E,29E,31E)-17-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-1,3,5,7,33,37-hexahydroxy-18-methyl-9,13,15-trioxo-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate (1)
(1E,3Z)-buta-1,3-diene-1,2,4-tricarboxylate (1)
(1R)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-7-ol (1)
(1R)-1-[[(2S,3R,11bS)-3-ethyl-9,10-dimethoxy-1,2,3,4,5,6,7,11b-octahydrobenzo[a]quinolizin-5-ium-2-yl]methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-2-ium-6-ol (1)
(1R,10R)-5-amino-14-oxido-14-oxo-13,15,18-trioxa-2,4,6,9-tetraza-14lambda5-phosphatetracyclo[8.8.0.03,8.012,17]octadeca-3(8),4-diene-7,11-dione (1)
(1R,14R,24S)-24-Methoxy-5,7,19,21,25-pentaoxa-13-azahexacyclo[12.11.0.02,10.04,8.015,23.018,22]pentacosa-2,4(8),9,15(23),16,18(22)-hexaene (1)
(1R,2'S,3'aS,12S,14S)-2',12-dimethylspiro[13-oxa-2,10,17-triazatetracyclo[10.3.2.02,11.04,9]heptadeca-4,6,8,10-tetraene-14,4'-3,3a-dihydro-2H-imidazo[1,2-a]indole]-1',3,16-trione (1)
(1R,2R,5R,8R,9S,10R,11S)-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadecane-9-carboxylate (1)
(1R,2R,5S,8S,9S,10R,11R,12R,13S)-5,12,13-trihydroxy-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadecane-9-carboxylate (1)
(1R,2R,6R,11S,13S,14R,21R)-7,19,23-Triazahexacyclo[9.9.1.11,13.12,6.07,21.014,19]tricosane (1)

First Public Date

2025 (99)
2026 (86)
2023 (73)
2024 (65)
2022 (58)
2020 (52)
2021 (50)
2019 (35)
2017 (32)
2018 (21)
2014 (20)
2016 (10)
2015 (7)
2013 (1)

Study type

Transcription profiling by array (61)
RNA-seq of coding RNA (27)
RNA-seq of coding RNA from single cells (8)
ChIP-seq (4)
Cell line - Single-cell sequencing (1)
Baseline (1)
Unknown experiment type (1)
Animal - High-throughput sequencing (1)
MicroRNA profiling by high throughput sequencing (1)
Comparative genomic hybridization by array (1)
Other (1)
MicroRNA profiling by array (1)
Proteomic profiling by array (1)
RNA-seq of total RNA (1)

Release Date

2023 (144)
2024 (125)
2022 (124)
2025 (118)
2020 (105)
2021 (93)
2019 (74)
2017 (72)
2016 (70)
2018 (64)
2014 (60)
2015 (42)
2026 (22)
2013 (16)
2012 (15)
2009 (10)
2008 (9)
2010 (8)
2011 (7)
2007 (7)
2006 (1)
2005 (1)
2004 (1)
2003 (1)
2002 (1)
1999 (1)

Lab affiliation

1) Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute, Jena, Germany 2) Department of Microbiology and Molecular Biology, Friedrich Schiller University, Jena, Germany (1)
Beijing University of Chinese Medicine, School of Traditional Chinese Medicine, Attending Physician, Assistant Researcher (1)
Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong (1)
Department of Immunology, University of Toronto, Canada Toronto General Hospital Research Institute, University Health Network, Canada (1)
Department of Immunology, University of Toronto, Canada Toronto General Hosptial Research Institute, University Health Network, Canada (1)
Department of Molecular Biology and Genetics, Aarhus University, Denmark. (1)
Department of Physiology, Wuhan University TaiKang Medical School (School of Basic Medical Sciences), Wuhan, China. (1)
Developmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute,University of Bonn; 53115 Bonn, Germany (1)
Institute of Biomedicine, Department of Microbiology, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (1)
Lelie Dan Faulty of Pharmacy, Univerity of Toronto (1)
Max Planck Institute of Immunobiology and Epigenetics Proteomics Unit Stuebeweg 51 79108 Freiburg, Germany (1)
Medizinisches Proteom-Center, Ruhr-University Bochum and Department of Anesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Knappschaftskrankenhaus Bochum (1)
Molecular Biology and Biochemistry, Medical University of Graz (1)
Myeloid Cell Immunology Institute of Experimental Immunology University of Zurich Switzerland (1)
Professor of Glycoimmunology (1)
Professor, Department of Obstetrics and Gynecology, University of South Florida, Tampa, Florida, USA (1)
Proteomics Center, Erasmus MC (1)
Proteomics Core Facility, University of Gothenburg (1)

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GSDME-controlled pyroptosis promotes muscle repair by coordinating tissue resident macrophages and fibro-adipogenic progenitors

GSDME (Gasdermin E) is a critical protein known for its role in pyroptosis, a form of programmed cell death associated with inflammation. We demonstrated that GSDME as a crucial mediator in muscle repair, particularly in the context of muscle damage induced by cardiotoxin (CTX). Specifically, we fou...

2026-01-05 | MTBLS10509 | MetaboLights

Differentiation and specification of resident tissue macrophages [MARS-seq]

Tissue resident macrophages are functionally diverse cells that share an embryonic mesodermal origin. However, the mechanism(s) that control their specification remain unclear. We performed transcriptional, molecular and in situ spatio-temporal analyses of macrophage development in mice. We report t...

ORGANISM(S): Mus musculus

2016-08-08 | E-GEOD-81760 | biostudies-arrayexpress

Differentiation and specification of resident tissue macrophages [SMART-Seq2]

ORGANISM(S): Mus musculus

2016-08-08 | E-GEOD-81686 | biostudies-arrayexpress

Differentiation and specification of resident tissue macrophages [ID3-KO RNA-seq]

ORGANISM(S): Mus musculus

2016-08-08 | E-GEOD-83854 | biostudies-arrayexpress

C-Myb+ erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages

Although classified as hematopoietic cells, tissue-resident macrophages are selfrenewing and maintained independently of adult hematopoiesis. While most macrophages originate from embryonic precursors that seed tissues prior to birth, their exact origin is unknown. Using an in utero macrophage deple...

ORGANISM(S): Mus musculus

2015-04-23 | E-GEOD-66970 | biostudies-arrayexpress

Mouse tissue-resident macrophage expression profiles

We show that macrophages from murine spleen, liver and peritoneum display dramatically different expression profiles. Clusters of genes were found to represent unique biological functions related to adhesion, antigen presentation, phagocytosis, lipid metabolism and signal transduction. Some gene fam...

ORGANISM(S): Mus musculus

2010-09-22 | E-GEOD-24258 | biostudies-arrayexpress

Expression data from wild type and Gata6-deficient tissue resident peritoneal macrophages

Tissue resident macrophages are notoriously heterogeneous, exhibiting discrete phenotypes as a consequence of tissue- and micro-anatomical niche-specific functions, but the molecular basis for this is not understood. We resolved a restricted transcriptional profile for the self-renewing population o...

ORGANISM(S): Mus musculus

2014-05-09 | E-GEOD-47049 | biostudies-arrayexpress

Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment [RNA-seq]

Macrophages are hematopoietic cells critical for innate immune defense, but also control organ homeostasis in a tissue-specific manner. Tissue-resident macrophages, therefore, provide a well-defined model to study the impact of ontogeny and microenvironment on chromatin state. Here, we profile the d...

ORGANISM(S): Mus musculus

2014-12-05 | E-GEOD-63340 | biostudies-arrayexpress

Homeostatic skin contains two different subsets of resident macrophages with distinct origin and gene profile.

We have found the existence of two independent populations contributing to the skin-resident macrophage pool based on their different origin. We have analyzed their gene profile by deep-sequencing (RNA-Seq). Analysis of RNA-Seq data revealed a differential expression signature between both subsets o...

ORGANISM(S): Mus musculus

2016-07-26 | E-GEOD-50566 | biostudies-arrayexpress

Bone marrow-derived and resident liver macrophages display unique transcriptomic signatures but similar biological functions

Liver macrophages play a major role in the control of infections in the liver and in the pathology associated with chronic liver diseases. It was recently shown that liver macrophages can have two different origins, however, the extent to which these populations are functionally distinct remains to ...

ORGANISM(S): Mus musculus

2016-07-28 | E-MTAB-4954 | biostudies-arrayexpress

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