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Mass spectrometry-based immunopeptidomics enables the comprehensive identification of major histocompatibility complex (MHC) peptides from cell culture as well as from tissue or tumor samples and is increasingly applied for the identification of tumor-specific and viral T-cell epitopes. Although mas...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-11-07 | PXD034017 | Pride
The objective of this study was to examine changes in muscle gene expression of growing bulls during a period of dietary energy restriction followed by a period of subsequent realimentation and compensatory growth. Purebred Holstein Friesian bulls (n=20) were assigned to one of two feeding treatment...
ORGANISM(S): Bos taurus 
MicroRNAs (miRNAs) regulate many basic aspects of cell biology including neuronal plasticity, but little is known of their roles in drug addiction. Extended access to cocaine can trigger the emergence of compulsive drug-seeking behaviors, but molecular mechanisms regulating this process remain uncle...
ORGANISM(S): Rattus norvegicus 
By using high-density oligonucleotide arrays, we profiled gene expression in reward-related brain regions of rats that developed escalated cocaine intake after extended access to cocaine (6 h per day). Rats allowed restricted daily access to cocaine (only 1 h) that displayed a stable level of cocain...
ORGANISM(S): Rattus norvegicus 
Moderate caloric restriction (CR) and weight loss are beneficial for the promotion of health; however, there is controversy regarding the effects of dieting regimens on behavior. In this study, we investigated two different dieting regimens: repeated fasting and refeeding (RFR) and daily feeding of ...
ORGANISM(S): Mus musculus 
Multi-tissue transcriptional response following acute caloric restriction in mice.
ORGANISM(S): Mus musculus 
Proteomic dataset of 15 murine kidneys of 14-week-old male C57Bl6 mice. Mice were divided into 3 treatment groups four weeks prior to nephrectomy and 5 mice had ad libitum access to food and water, while another 10 mice received 30% food restriction. Calorically restricted mice either received intra...
ORGANISM(S): Mus musculus (Mouse) 
2022-06-17 | PXD031604 | Pride
The experiment aims at a characterization of gene expression changes in duodenum during caloric restriction. The C57BL6 mice were restricted their food intake to 75% of their normal daily portion. The food was delivered daily around 4-6pm for 14 days. The mice were housed with free access to water. ...
ORGANISM(S): Mus musculus 
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