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UnknownPointBreak: a randomized phase III study of pemetrexed plus carboplatin and bevacizumab followed by maintenance pemetrexed and bevacizumab versus paclitaxel plus carboplatin and bevacizumab followed by maintenance bevacizumab in patients with stage IIIB or IV nonsquamous non-small-cell lung cancer.
Not available
S-EPMC4881367 | biostudies-literature
TranscriptomicsRegulation of Transcription Termination by Glucosylated Hydroxymethyluracil, Base J, in L. major and T. brucei
Base J, β-D-glucosyl-hydroxymethyluracil, is an epigenetic modification of thymine in the nuclear DNA of flagellated protozoa of the order Kinetoplastida. J is enriched at sites involved in RNA Polymerase (RNAP) II initiation and termination. We have previously demonstrated a role of J in regulating...
ORGANISM(S): Trypanosoma brucei 
2015-05-18 | E-GEOD-57621 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of P. aeruginosa PA01 grown with or without human LL37
Five biological repeats of P.aeruginosa PAO1 in the absence of human LL37 and five biological repeats of P.aeruginosa presence of LL37 were grown in mineral medium in continuous-culture flow cells. Microarray experiments were done using microarray slides and protocols from TIGR on cells harvested f...
ORGANISM(S): Pseudomonas aeruginosa 
2008-10-25 | E-FPMI-12 | biostudies-arrayexpress
UnknownWWTR1(TAZ)-CAMTA1 gene fusion is sufficient to dysregulate YAP/TAZ signaling and drive epithelioid hemangioendothelioma tumorigenesis.
Not available
S-EPMC8015722 | biostudies-literature
TranscriptomicsBase J represses genes at the end of polycistronic gene clusters in Leishmania major by promoting RNAP II termination
Base J and H3.V promote RNA Polymerase (RNAP) II termination within polycistronic gene clusters in the kinetoplastid species Trypanosoma brucei. Although base J has been shown to promote RNAP II termination in the related kinetoplastid species Leishmania major and Leishmania tarentolae, the role of ...
ORGANISM(S): Leishmania major 
2016-07-20 | E-GEOD-77632 | biostudies-arrayexpress
UnknownOutcome after surgery alone or with restricted use of chemotherapy for patients with low-risk neuroblastoma: results of Children's Oncology Group study P9641.
Not available
S-EPMC3383182 | biostudies-literature
UnknownRepurposing Clemastine to Target Glioblastoma Cell Stemness.
Not available
S-EPMC10526458 | biostudies-literature
TranscriptomicsMolecular characterization of adult mouse subventricular zone progenitor cells during the onset of differentiation
Adult mouse subventricular zone (SVZ) neural progenitor cells (NPCs) retain the capacity to generate multiple lineages in vitro and in vivo. Thus far, the mechanisms involved in the regulation of these cells have not been well elucidated. We have carried out RNA profiling of adult SVZ cell cultures ...
ORGANISM(S): Mus musculus 
2010-07-01 | E-GEOD-4496 | biostudies-arrayexpress
UnknownVaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma.
Not available
S-EPMC3139394 | biostudies-literature
TranscriptomicsThe Snf1-Related Kinase, Hunk, Is Essential for Mammary Tumor Metastasis
We previously identified a novel SNF1/AMPK-related protein kinase, Hunk, from a mammary tumor arising in an MMTV-neu transgenic mouse. The function of this kinase is unknown. Using targeted deletion in mice, we now demonstrate that Hunk is required for the metastasis of c-myc-induced mammary tumors,...
ORGANISM(S): Mus musculus 
2009-12-31 | E-GEOD-14226 | biostudies-arrayexpress
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