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TranscriptomicsTranscriptomic analysis of human retinal detachment (RD) reveals both inflammation and photoreceptor death
We have used surgical specimens to perform a differential analysis of the transcriptome of human retinal tissues following detachment. Data analysis reveals major involvement of the immune response in the disease and interindividual variation was monitored to unravel a second crucial aspect of the p...
ORGANISM(S): Homo sapiens 
2012-03-06 | E-GEOD-28133 | biostudies-arrayexpress
ProteomicsComparative Proteomic Analysis of Human Vitreous in Rhegmatogenous Retinal Detachment and Diabetic Retinopathy
The vitreous humor can provide important information about physiological and pathophysiological processes within the eye, particularly concerning the retina. Despite the widespread prevalence of various vitreoretinal diseases, that can ultimately lead to blindness, there is not a clear understanding...
ORGANISM(S): Homo sapiens (Human) 
2025-02-24 | PXD050611 | Pride
Diabetic retinopathy Human vitreous humor Rhegmatogenous retinal detachment 
ProteomicsALTERED PATTERN OF PROTEOLYSIS OF EXTRACELLULAR PROTEINS IN RHEGMATOGENOUS RETINAL DETACHMENT BY MINING OF TRYPTIC AND N-TERMINI DATASETS FROM VITREOUS HUMOR PROTEOME
Retinal detachment is a severe eye condition characterized by the detachment of the neurosensory retina from the retinal pigment epithelium and caused by retinal tears. Pars plana vitrectomy is the elective surgical procedure during which vitreous humor, a fluid which shapes the eye globe and suppor...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PXD057155 | Pride
Eye Vitreous humor Uhplc-ms Ocular fluids Dda 
ProteomicsAqueous Proteomics of Recurrent Rhegmatogenous Retinal Detachment
The aqueous collected during primary surgery of 13 patients suf-fering RRD (RRD group) was compared to 11 age and sex-matched patients successfully operated for rhegmatogenous RD with no recurrency after 12-months follow-up (noRRD Group), regardless of surgical technique.
ORGANISM(S): Homo sapiens (Human) 
2026-06-01 | PXD070155 | Pride
Human Aqueous humor Hplc-ms 
ProteomicsMolecular pathogenesis of rhegmatogenous retinal detachment
Here, we performed molecular pathology analysis of the vitreous proteomes collected from 127 patients with RRD using SWATH-mass spectrometry. For comparison, samples of neurodegenerative vitreoretinal interface eyes (MH, Pucker) and proliferative diabetic retinopathy eyes with tractional-retinal det...
ORGANISM(S): Human 
2020-11-05 | MSV000086412 | MassIVE
UnknownFactors associated with postoperative visual function after rhegmatogenous retinal detachment with foveal detachment.
Not available
S-EPMC11414927 | biostudies-literature
UnknownReticular Pseudodrusen Voids after Rhegmatogenous Retinal Detachment.
Not available
S-EPMC10601779 | biostudies-literature
ProteomicsThe baseline vitreous proteome in rhegmatogenous retinal detachment: a case–control study of proliferative vitreoretinopathy
Quantitative proteomic analysis of undiluted human vitreous biopsies collected at the time of primary surgical repair of rhegmatogenous retinal detachment (RRD), comparing patients who later developed proliferative vitreoretinopathy (PVR; n=8) with matched RRD controls who did not (n=8). Vitreous sa...
ORGANISM(S): Homo sapiens (Human) 
2026-05-05 | PXD077831 | Pride
Pvr Tmt-10-plex Proteomics Vitreous Ocular Retinal detachment Biomarker Proliferative vitreoretinopathy 
UnknownGenetic and clinical profile of high myopia patients with rhegmatogenous retinal detachment.
Not available
S-EPMC12014733 | biostudies-literature
ProteomicsProtein composition of the subretinal fluid suggest selective diffusion of vitreous proteins in retinal detachment
Purpose: To study the proteome of the subretinal fluid (SRF) from rhegmatogenous retinal detachment (RRD) in search for novel markers for improved diagnosis and prognosis of RRD. Methods: Human undiluted SRF obtained during vitrectomy for primary RRD using a 41G needle (n = 24) was analyzed and comp...
ORGANISM(S): Homo sapiens (Human) 
2020-10-20 | PXD019159 | Pride
Retinal detachment Subretinal fluid Vitreous humor Eye 
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