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GenomicsSystematic study of mammalian RhoGAPs and GEFs
Systematic study of mammalian RhoGAPs and GEFs and their role in regulating Rho signalling
PRJEB27183 | ENA
UnknownFixing the GAP: The role of RhoGAPs in cancer.
Not available
S-EPMC9081277 | biostudies-literature
ProteomicsRhoGAP/GEF Interactome - In this project we cloned 141 mammalian RhoGAPs/GEFs (112 human, 26 mouse, 2 rat, 1 chimpanzee) and performed a systematic study of their interactome, localisation and specificity. Here we submit the mass spectrometry data from the interactome screen.
In this project we cloned 141 mammalian RhoGAPs/GEFs (112 human, 26 mouse, 2 rat, 1 chimpanzee) and performed a systematic study of their interactome, localisation and specificity. Here we submit the mass spectrometry data from the interactome screen.
ORGANISM(S): Pan troglodytes (Chimpanzee) Homo sapiens (Human) Mus musculus (Mouse) Rattus norvegicus (Rat) 
2020-01-21 | PXD010144 | Pride
Mammalian Interactome Rhogaps Rho signaling Rhogefs 
UnknownRPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availability.
Not available
S-EPMC6960015 | biostudies-literature
ProteomicsRhoGAP/GEF interactome - We performed a systematic study of 141 mammalian RhoGAPs and GEFs including their interactome, specificity and localisation. Here we submit the data from the interactome screen that were processed using MaxQuant.
We performed a systematic study of 141 mammalian RhoGAPs and GEFs including their interactome, specificity and localisation. Here we submit the data from the interactome screen that were processed using MaxQuant.
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2020-01-21 | PXD010084 | Pride
Rho signaling Rhogap Rhogef Interactome 
TranscriptomicsSystems Modeling of the Rho Signaling Network
Describing the architecture of robust, nonlinear cell signaling networks is essential to gain a predictive understanding of cellular behavior. The structure of the Drosophila Rho-signaling network, comprised of Rho-family GTPases, RhoGTP Exchange Factors (RhoGEFs), and RhoGTPase Activating Proteins...
ORGANISM(S): Drosophila melanogaster 
2012-12-31 | E-GEOD-18307 | biostudies-arrayexpress
UnknownRNAi screens for Rho GTPase regulators of cell shape and YAP/TAZ localisation in triple negative breast cancer.
Not available
S-EPMC5332010 | biostudies-literature
UnknownDeciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.
Not available
S-EPMC5034035 | biostudies-literature
ProteomicsConvergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps
Gene duplication, accompanied by modification of the expression and/or function of one of the duplicates under the action of positive selection, followed by further duplication to produce multigene families of toxins is a well-documented process in venomous animals. This evolutionary model has been ...
ORGANISM(S): Leptopilina boulardi Leptopilina heterotoma 
2023-06-09 | PXD041695 | Pride
Gene duplication Venom Evolution Positive selection Parasitoids Rhogap Ovarian calyx 
UnknownA Structural Network Analysis of Neuronal ArhGAP21/23 Interactors by Computational Modeling.
Not available
S-EPMC10249030 | biostudies-literature
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