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ProteomicsIdentification and characterization of a ribosome receptor for starvation-induced ribophagy
The lysosome degrades and recycles macromolecules, signals to the master growth regulator mTORC1, and is associated with human disease. Here, we performed quantitative proteomic analyses of lysosomes rapidly isolated using the LysoIP method and find that nutrient levels and mTOR dynamically modulate...
ORGANISM(S): Homo sapiens (Human) 
2018-06-21 | PXD009084 | Pride
Lysosome Ribophagy Mtor 
GenomicsA chemical inducer of ribophagy limits the toxicity of ALS-related arginine-rich peptides
A chemical inducer of ribophagy limits the toxicity of ALS-related arginine-rich peptides
PRJNA1436989 | ENA
UnknownNuclear fragile X mental retardation-interacting protein 1-mediated ribophagy protects T lymphocytes against apoptosis in sepsis
Not available
S-EPMC9976742 | biostudies-literature
TranscriptomicsA chemical inducer of ribophagy limits the toxicity of ALS-related arginine-rich peptides
9ORF72 intronic repeat expansions are the most frequent mutation found in Amyotrophic Lateral Sclerosis (ALS), producing toxic arginine-rich dipeptides (DPR) that disrupt RNA metabolism and trigger orphan ribosomal protein (RP) accumulation. Through a large phenotypic chemical screen, we identified ...
ORGANISM(S): Homo sapiens 
2026-03-23 | GSE324761 | GEO
UnknownCdc48 and Ufd3, new partners of the ubiquitin protease Ubp3, are required for ribophagy.
Not available
S-EPMC2897114 | biostudies-literature
UnknownNUFIP1-Mediated Ribophagy Alleviates PANoptosis of CD4<sup>+</sup> T Lymphocytes in Sepsis via the cGAS-STING Pathway.
Not available
S-EPMC12454940 | biostudies-literature
UnknownNUFIP1 is a ribosome receptor for starvation-induced ribophagy.
Not available
S-EPMC6020066 | biostudies-literature
UnknownSystematic analysis of ribophagy in human cells reveals bystander flux during selective autophagy.
Not available
S-EPMC5786475 | biostudies-literature
UnknownDeubiquitinase Ubp3 regulates ribophagy and deubiquitinates Smo1 for appressorium-mediated infection by Magnaporthe oryzae.
Not available
S-EPMC9104258 | biostudies-literature
UnknownNuclear fragile X mental retardation-interacting protein 1-mediated ribophagy regulates immune function of dendritic cells in polymicrobial sepsis.
Not available
S-EPMC12448799 | biostudies-literature
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