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Soybean oil consumption is increasing worldwide and parallels the rise in obesity. Rich in unsaturated fats, especially linoleic acid, soybean oil is assumed to be healthy, and yet it induces obesity, diabetes, insulin resistance and fatty liver in mice. Here, we show that the genetically modified s...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-06-08 | MSV000081149 | MassIVE
The CRP-family transcription factor NtcA, universally found in cyanobacteria, was initially discovered as a regulator operating N control. It responds to the N regime signaled by the internal 2-oxoglutarate levels, an indicator of the C to N balance of the cells. NtcA-activated canonical promoters b...
ORGANISM(S): Anabaena 
The transcriptional regulator TrmBL1 from the hyperthermophilic euryarchaeon Pyrococcus furiosus functions as repressor as well as activator of genes encoding enzymes mainly involved in sugar uptake, glykolysis and gluconeogenesis. The aim of this study was to explore the genome-wide binding sites o...
ORGANISM(S): Pyrococcus furiosus DSM 3638 
Pervasive Transcription originates from spurious promoters present in both orientations within coding sequences. Spurious transcripts are typically untranslated and thus for the most part are terminated by transcription termination factor Rho. They can be studied by impairing Rho activity, which in ...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 
Locally advanced head and neck squamous cell carcinomas (HNSCC) are commonly treated with chemoradiotherapy (CRT) or induction chemotherapy followed by radiotherapy/CRT or surgery. The purpose of our study was to identify expression signatures and molecular markers able to anticipate tumor response ...
ORGANISM(S): Homo sapiens 
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