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TranscriptomicsGene expression of murine B cells activated via TLR4 or TLR4 + CD40: Group1 naM-CM-/ve B cells, Group2 LPS activated B cells 24h, Group3 LPS + anti-CD40 activated B cells 24h, Group4 LPS activated B cells 72h, and Group5 LPS + anti-CD40 activated B cells 72h.
Murine B cells can be activated via the surface receptors TLR4 and CD40. For a global assessment of differences in gene expression between these two different modes of B cell activation a genome wide transcriptome analysis was performed. In order to dissect different gene expression profiles of B ce...
ORGANISM(S): Mus musculus 
2014-02-24 | E-GEOD-35998 | biostudies-arrayexpress
ProteomicsUnexpected role of a truncated ribosome-associated chloroplast trigger factor homolog serving ribosome biogenesis in plants - Data set 2: Analysis of sedimented ribosomes
Molecular chaperones are essential throughout a protein's life and act already during protein synthesis. Bacteria and chloroplasts of plant cells share the ribosome-associated chaperone trigger factor (Tig1 in plastids), facilitating maturation of emerging nascent polypeptides. While typical trigger...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-12-09 | PXD057264 | Pride
Ribosomes Chaperones Arabidopsis 
ProteomicsUnexpected role of a truncated ribosome-associated chloroplast trigger factor homolog serving ribosome biogenesis in plants - Data set 1 (Global proteome of wt and tig2 mutants)
Molecular chaperones are essential throughout a protein's life and act already during protein synthesis. Bacteria and chloroplasts of plant cells share the ribosome-associated chaperone trigger factor (Tig1 in plastids), facilitating maturation of emerging nascent polypeptides. While typical trigger...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-12-09 | PXD057252 | Pride
Chaperone Arabidopsis 
ProteomicsFast and global reorganization of the chloroplast protein biogenesis network during heat acclimation
Heat waves caused by global warming severely challenge photosynthesis and hence plant biomass production, but the mechanisms of its adjustment, repair and biogenesis during heat acclimation are elusive. We provide a global and time-resolved insight, how these processes are modulated during heat accl...
ORGANISM(S): Chlamydomonas reinhardtii 
2022-01-06 | PXD024949 | Pride
Photosynthesis biogenesis Protein complex assembly Translational regulation Protein synthesis Heat acclimation Chloroplast 
ProteomicsThe proteomic inventory reveals the chloroplast ribosome as nexus within a diverse protein network - Effect of Crosslinking
In plant cells, chloroplast gene expression is predominantly controlled through regulationof translation. Fine-tuning of protein synthesis is vital for plant development, acclimation to environmental challenges and for the assembly of major protein complexes such as the photosynthesis machinery. How...
ORGANISM(S): Chlamydomonas reinhardtii 
2020-11-23 | PXD022210 | Pride
Chlamydomonas Plastide ribosome Ae-ms Lc-ms/ms 
UnknownFunctional apoptosis profiling reveals vulnerabilities in T-cell large granular lymphocytic leukemia.
Not available
S-EPMC11868225 | biostudies-literature
UnknownDiscovery of molecularly-informed therapeutic strategies for mature T-cell leukemias and lymphomas.
Not available
S-EPMC12552946 | biostudies-literature
UnknownVitrectomy outcomes in eyes with diabetic macular edema and vitreomacular traction.
Not available
S-EPMC2911350 | biostudies-literature
UnknownA randomized trial comparing intravitreal triamcinolone acetonide and focal/grid photocoagulation for diabetic macular edema.
Not available
S-EPMC2748264 | biostudies-literature
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