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TranscriptomicsTranscription profiling of right ventricule from arrhythmogenic heterozygous plakoglobin deficient mice undergone endurance training to identify transcriptional responses to training.
Endurance training accelerated development of right ventricular dysfunction and arrhythmias in plakoglobin+/- mice. Histology and electron microscopy did not identify right ventricular abnormalities. To identify differences in the transcriptional response to training gene expression profiling was pe...
ORGANISM(S): Mus musculus 
2007-11-06 | E-GEOD-4120 | biostudies-arrayexpress
TranscriptomicsGene expression in the right ventricle of Rattus norvegicus during development of right ventricular heart failure and treatment
Right ventricular heart failure (RVF) associated with pulmonary hypertension (PH) is characterized by a distinct gene expression pattern when compared with functional compensatory hypertrophy. Carvedilol treatment after RVF has been established reduces right ventricle (RV) hypertrophy and improves...
ORGANISM(S): Rattus norvegicus 
2013-05-06 | E-GEOD-42579 | biostudies-arrayexpress
ProteomicsMyeloid cell recruitment propels right ventricular dysfunction in HFpEF via sterile inflammation
This project characterizes chamber-specific proteomic remodeling in a murine three-hit HFpEF model that develops right ventricular dysfunction, using chow, hypoxia alone, and HFD+L-NAME as control conditions. The three-hit model (hypoxia, high-fat diet, and L-NAME) recapitulates key features of huma...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-07 | PXD074772 | Pride
Heart Mouse Hfpef Hypoxia 
ProteomicsProteomic analysis of right-ventricular dysfunction (RVD) in patients with advanced chronic heart failure.
This research aimed to identify protein biomarkers of right ventricular dysfunction in patients with advanced heart failure with reduced ejection fraction (HFrEF). Samples of myocardium from both, right and left ventricles (RV, LV) were obtained from 10 HFrEF patients with right ventricular dysfunct...
ORGANISM(S): Homo sapiens (Human) 
2025-02-11 | PXD043768 | Pride
Myocardium Right ventricular dysfunction Lfq Triton x-100 Chronic heart failure Biomarkers Rvd 
TranscriptomicsExpression data from human heart right ventricular wall
Gene expression in the right ventricle is different in control patients as compared to either idiopathic dilated cardiomyopathy or pulmonary arterial hypertension Two human hearts obtained at autopsy from each of control, pulmonary hypertension, and dilated cardiomyopathy
ORGANISM(S): Homo sapiens 
2015-04-02 | E-GEOD-67492 | biostudies-arrayexpress
ProteomicsEffect of GP130 Antagonism on Microtubule Associated Proteins
TMT10plex analysis of microtubule associated proteins from right ventricular extracts of 3 control rats, 3 monocrotaline rats, and 4 monocrotaline rats treated with the GP130 antagonist SC144.
ORGANISM(S): Rattus Norvegicus (ncbitaxon:10116) 
2021-07-19 | MSV000087852 | MassIVE
TranscriptomicsMutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy
Left ventricular noncompaction (LVNC) Causes prominent ventricular trabeculations and reduces cardiac systolic function. The clinical presentation of LVNC ranges from asymptomatic to heart failure. We show that germline mutations in human MIB1 (mindbomb homolog 1), which encodes an E3 ubiquitin liga...
ORGANISM(S): Mus musculus 
2015-08-10 | E-GEOD-71912 | biostudies-arrayexpress
GenomicsDevelopment of Specific Therapy Against Right Ventricular Failure
Development of Specific Therapy Against Right Ventricular Failure
PRJNA761093 | ENA
GenomicsFormyl peptide receptor 2 determines sex differences in pulmonary hypertension-associated right ventricular dysfunction
Formyl peptide receptor 2 determines sex differences in pulmonary hypertension-associated right ventricular dysfunction
PRJNA1222414 | ENA
TranscriptomicsLeft ventricular myocardial transcriptomic profiling for target discovery in a rat model of pressure overload-induced heart failure
Left ventricular myocardial transcriptomic profiling was performed in rats subjected to transverse aortic constriction (TAC)-induced heart failure and sham-operated controls to investigate gene expression changes associated with pressure overload-induced cardiac remodeling. The dataset was used in s...
ORGANISM(S): Rattus norvegicus 
2026-06-11 | E-MTAB-17114 | biostudies-arrayexpress
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