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ProteomicsProteogenomic Discovery of Neoantigens Facilitates Personalized Multi-antigen Targeted T cell Immunotherapy for Brain Tumors
Neoantigen discovery in pediatric brain tumors is hampered by their low mutational burden and scant tissue availability. We developed a low-input proteogenomic approach combining tumor DNA/RNA sequencing and mass spectrometry proteomics to identify tumor-restricted (neoantigen) peptides arising from...
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD029082 | Pride
Lc-msms Medulloblastoma Pediatric brain tumors 
ProteomicsProteogenomic Analysis of Medulloblastoma
In order to investigate medulloblastoma biology via its proteome, we undertook a super-SILAC quantitative proteomics survey using 41 clinical tissue samples spanning the 4 genomic subgroups and control cerebellum
ORGANISM(S): Homo sapiens (Human) 
2018-06-10 | PXD008750 | Pride
Medulloblastoma Brain tumor Silac Human Pediatrics 
UnknownInhibiting Arginine Methylation as a Tool to Investigate Cross-Talk with Methylation and Acetylation Post-Translational Modifications in a Glioblastoma Cell Line.
Not available
S-EPMC6313862 | biostudies-literature
TranscriptomicsInhibition of the mitochondrial TCA cycle by monofluoroacetate in Arabidopsis thaliana
Plant mitochondria signal to the nucleus leading to altered transcription of nuclear genes by a process called mitochondrial retrograde regulation (MRR). MRR is implicated in metabolic homeostasis and responses to stress conditions. Transcriptional consequences on nuclear gene expression of mitochon...
ORGANISM(S): Arabidopsis thaliana 
2013-01-01 | E-GEOD-29268 | biostudies-arrayexpress
TranscriptomicsInhibition of the mitochondrial electron transport chain by antimycin A in Arabidopsis thaliana
Plant mitochondria signal to the nucleus leading to altered transcription of nuclear genes by a process called mitochondrial retrograde regulation (MRR). MRR is implicated in metabolic homeostasis and responses to stress conditions. Transcriptional consequences on nuclear gene expression of mitochon...
ORGANISM(S): Arabidopsis thaliana 
2013-01-01 | E-GEOD-29204 | biostudies-arrayexpress
TranscriptomicsArabidopsis transcriptome responses to mitochondrial perturbations
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Arabidopsis thaliana 
2013-01-01 | E-GEOD-29269 | biostudies-arrayexpress
UnknownEfficacy and Safety of Degludec versus Glargine in Type 2 Diabetes.
Not available
S-EPMC5731244 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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