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The analysis of RNA-protein interactomes indicates that the amount of structure in RNA molecules correlates with the capacity of binding to proteins in vitro and in vivo. To validate this observation, we used an in vitro network that mimics the composition of phase-separated RNA granules. The interf...
ORGANISM(S): Homo sapiens (Human) 
2019-09-13 | PXD011751 | Pride
Relapsed pediatric B-cell acute lymphoblastic leukemia (B-ALL) remains one of the leading causes of cancer mortality in children. Up to 20% of children will suffer relapse and face a poor prognosis. Our recent work on the evolution of the epigenetic landscape from diagnosis to relapse demonstrates b...
ORGANISM(S): Homo sapiens 
2024-05-01 | GSE222685 | GEO
Clonal evolution of the 3D chromatin landscape of relapsed ALL [RNA-seq]
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