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TranscriptomicsMycobacterium tuberculosis efpA CRISPRi knock-down transcriptional profile - induced efpA knock-down strain vs non-induced condition
In Mycobacterium tuberculosis, the efflux pump, EfpA, plays an essential but uncharacterised role in its physiology and antibiotic tolerance. In this study, an ATc-inducible CRISPR interference (CRISPRi) system was introduced into M. tuberculosis to knock-down the expression of efpA and determine an...
ORGANISM(S): Mycobacterium tuberculosis 
2024-06-19 | E-MTAB-13755 | biostudies-arrayexpress
TranscriptomicsChromatin immunopreciptation genome wide location of H2A.Z binding sites in yeast yeast
genome wide location of H2A.Z binding sites in yeast Saccharomyces cerevisiae. Nucleosome density controled with H2B ChIP. Hybridization control ChIP H2AZ/H2AZ and H2A/H2B.
ORGANISM(S): Saccharomyces cerevisiae 
2005-12-31 | E-MEXP-396 | biostudies-arrayexpress
ProteomicsThe N-myristoylome of Trypanosoma cruzi.
Identification of N-myristoylated proteins in Trypanosoma cruzi using a chemically tractable myristic acid analogue, azidomyristate. Enrichment of labelled proteins was carried out prior to identification by LC-MSMS
ORGANISM(S): Trypanosoma cruzi 
2016-08-08 | PXD002970 | Pride
N-myristoylation N-myristoyltransferase Trypanosoma cruzi Click chemistry 
MetabolomicsRare and common genetic determinants of metabolic individuality and their effects on human health (INTERVAL study assays)

Garrod’s concept of “chemical individuality” has contributed to comprehension of the molecular origins of human diseases. Untargeted high-throughput metabolomic technologies provide an in-depth snapshot of human metabolism at scale. We studied the genetic architecture of the human plasma metabolo...

2022-09-09 | MTBLS834 | MetaboLights
TranscriptomicsClassification of a frameshift/extended and a stop mutation in WT1 as gain of function mutations which activate cell cycle genes and promote Wilms tumor cell proliferation
The Wilms tumor 1 (WT1) gene encodes a zinc finger transcription factor important for normal kidney development. WT1 is a suppressor for Wilms tumor development and an oncogene for diverse malignant tumors. We recently established cell lines from primary Wilms tumors and identified the corresponding...
ORGANISM(S): Homo sapiens 
2014-05-12 | E-GEOD-54635 | biostudies-arrayexpress
UnknownSocial and ecological complexity is associated with gestural repertoire size of wild chimpanzees.
Not available
S-EPMC7383666 | biostudies-literature
ProteomicsAllotype-specific processing of the CD16a N45-glycan from primary human natural killer cells and monocytes
Two datasets that contain the less common CD16a H48 allele
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-01-13 | MSV000084795 | MassIVE
ProteomicsSite-specific analysis of CD16a and CD32a N-glycosylation from monocytes display donor variability which modulate affinity to IgG1 Fc
Glycopeptide mass spectra of CD16a and CD32a from isolated monocytes display donor and site variability. CD16a N-glycosylation composition affects the affinity of IgG1 Fc. Peptide coverage of CD16a was ~85% while CD32a was ~61%.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-26 | MSV000084012 | MassIVE
UnknownThe effect of substrate and surface plasmons on symmetry breaking at the substrate interface of the topological insulator Bi2Te3.
Not available
S-EPMC6468116 | biostudies-literature
UnknownEvidence for the impact of the 8.2-kyBP climate event on Near Eastern early farmers.
Not available
S-EPMC6126735 | biostudies-literature
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