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MetabolomicsTreatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomics
Introduction: Obestatin is a controversial gastrointestinal peptide purported to have metabolic actions. Objectives: This study investigated whether treatment with a stable obestatin analogue (PEG-OB(Cys10, Cys13) changed plasma metabolite levels firstly in lean and subsequently in diet-induced obes...
2017-07-25 | MTBLS334 | MetaboLights
ProteomicsEnergetics- and transport-related protein abundance responds differentially to salt in Oryza australiensis roots
Salinity is a major constraint on agricultural productivity worldwide. Despite the serious impacts of salinity on rice yields, particularly in Asia, mechanisms of salt tolerance in wild rice species are yet to be explored. Here we extracted and quantified root microsomal proteins of Oryza australien...
ORGANISM(S): Oryza australiensis 
2019-09-11 | PXD013701 | Pride
Oryza sativa Rice Atpase Proteomics Oryza australiensis Transporters Energy metabolism Stress response Tolerance Tandem mass tags 
UnknownSubstantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: results of a phase I study of navitoclax in patients with relapsed or refractory disease.
Not available
S-EPMC4979082 | biostudies-literature
MetabolomicsFatty acid oxidation protects cancer cells from apoptosis through increasing mitochondrial membrane lipids

Overcoming resistance to chemotherapies remains a major unmet need for cancers such as triple negative breast cancer (TNBC). Therefore, mechanistic studies to provide insight for drug development are urgently needed to overcome TNBC therapy resistance. Recently, an important role of fatty acid β-...

2022-05-31 | MTBLS4709 | MetaboLights
UnknownA longitudinal assessment of diabetes autoantibodies in the SEARCH for diabetes in youth study.
Not available
S-EPMC9588609 | biostudies-literature
UnknownRediscovery of Ixodes confusus in Australia with the first description of the male from Australia, a redescription of the female and the mitochondrial (mt) genomes of five species of Ixodes.
Not available
S-EPMC8971345 | biostudies-literature
ProteomicsDetection of Cell-Cell Interactions via Photocatalytic Cell Tagging
The growing appreciation of immune cell-cell interactions within disease environments has led to significant efforts to develop highly effective protein- and cell-based immunotherapies. However, characterizing these complex cell-cell interfaces in high resolution remains challenging. Thus, technol...
ORGANISM(S): Bos taurus (Bovine) Oryctolagus cuniculus (Rabbit) Gallus gallus (Chicken) 
2022-06-03 | PXD032203 | Pride
Flavin-based photocatalysis Phenoxy radical generation Tyrosine labeling 
ProteomicsComparison of culture supernatants from wild-type Vibrio cholerae and a mutant lacking the PDZ domain of the type II secretion system
The culture supernatant of wild-type (WT) Vibrio cholerae N16961 and mutant epsC∆PDZ strains were compared to determine which, if any, type II secretion system substrates were affected by the deletion of the PDZ domain of EpsC
ORGANISM(S): Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) 
2025-08-25 | PXD062995 | Pride
Vibrio cholerae T2ss Pdz Protein secretion Gspc 
TranscriptomicsMulti-level omics analysis of dystrophin loss and therapeutic restoration in a murine model
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-09-24 | E-GEOD-64420 | biostudies-arrayexpress
UnknownHeat stress induced, ligand-independent MET and EGFR signalling in hepatocellular carcinoma.
Not available
S-EPMC6175538 | biostudies-literature
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