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TranscriptomicsTranscriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression (RNA-Seq data)
Noncoding RNAs (ncRNAs) are emerging as key molecules in human cancer, with the potential to serve as novel markers of disease and to reveal uncharacterized aspects of tumor biology. Here we discover 121 unannotated prostate cancerM-bM-^@M-^Sassociated ncRNA transcripts (PCATs) by ab initio assembly...
ORGANISM(S): Homo sapiens 
2011-08-02 | E-GEOD-25183 | biostudies-arrayexpress
GenomicsDNA Methylation Analysis of Prostate Cancer Cell Lines and Tissues Using Next Generation Sequencing

Aberrant DNA methylation changes are known to occur during prostate cancer progression beginning with precursor lesions. Utilizing fifty nanograms of genomic DNA in Methylplex-Next Generation Sequencing (M-NGS) we mapped the global DNA methylation patterns in prostate tissues (n=17) and cells (n=...

phs000597.v1.p1 | EGA
TranscriptomicsDual RNA-seq of parasite and host reveals gene expression dynamics during filarial worm-mosquito interactions
Parasite biology, by its very nature, cannot be understood without integrating it with that of the host, nor can the host response be adequately explained without considering the activity of the parasite. However, due to experimental limitations, molecular studies of parasite-host systems have been ...
ORGANISM(S): Aedes aegypti 
2014-04-15 | E-GEOD-53664 | biostudies-arrayexpress
GenomicsIntronic Non-CG DNA Hydroxymethylation and Alternative mRNA Splicing in Honey Bees
Honey bee non-CG DNA hydroxymethylation is enriched in the introns, which supplements previous findings that honey bee CG DNA methylation is enriched in exons. Bisulfite sequencing combined with Pvu-Seq to distinguish 5-methylcytosine from 5-hydroxymethylcytosine and RNA-Seq
ORGANISM(S): Apis mellifera scutellata 
2013-09-19 | E-GEOD-50990 | biostudies-arrayexpress
ProteomicsCrystalline cellulose hydrolysis in microbial communities via actinobacterial glycoside hydrolase family 12
Proteomic data from supernatants from thermophilic cellulolytic microbial communities, for the identification of specific hydrolases from Thermobispora bispora related actinobacterium.
ORGANISM(S): environmental samples 
2016-08-25 | PXD004204 | Pride
Proteomics Metaproteome Hydrolases Actinobacterium 
UnknownA study protocol for a multicenter randomized pilot trial of a dyadic, tailored, web-based, psychosocial, and physical activity self-management program (TEMPO) for men with prostate cancer and their caregivers.
Not available
S-EPMC7980105 | biostudies-literature
TranscriptomicsMultiple platform assessment and isomir analysis of the EGF dependent microRNA-ome by microarray and deep sequencing analysis [small RNA-seq]
We have used an integrative high content analysis approach to identify the specific miRNAs implicated in EGF signaling in HeLa cells as potential mediators of cancer mediated functions. We have used microarray and deep-sequencing technologies in order to obtain a global view of the EGF miRNA transcr...
ORGANISM(S): Homo sapiens 
2013-06-11 | E-GEOD-41359 | biostudies-arrayexpress
ProteomicsDichomitus squalens partially tailors its molecular responses to the composition of solid wood
The fungal response to compositional differences in softwood as measured by transcriptomics, proteomics and enzyme activities showed a partial tailoring to wood composition.
ORGANISM(S): Dichomitus squalens 
2019-04-09 | PXD009818 | Pride
Cazymes Softwood Dichomitus squalens White-rot fungi Hardwood 
ProteomicsIFITM3-mediated regulation of cell membrane dynamics is essential for malignant B-cell transformation
B cell receptor (BCR) signaling and oncogenic tyrosine kinases that mimic BCR-signaling in B-lineage leukemia and lymphoma depend on assembly of membrane proximal signaling complexes. Signalosomes in normal BCR- and oncogene (e.g. BCR-ABL1, RAS-pathway lesions) signal transduction are recruited to p...
ORGANISM(S): Mus musculus (Mouse) 
2020-12-18 | PXD014691 | Pride
Leukemia Bcr signaling Cell surface Lipid rafts 
TranscriptomicsProfiling of SF188 ATRX isogenic glioma cells
Methylation profiling of SF188 paediatric high grade glioma cell line isogenic clones carrying CRISR/Cas9 frameshift deletions in ATRX
ORGANISM(S): Homo sapiens 
2019-06-01 | E-MTAB-7800 | biostudies-arrayexpress
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