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ProteomicsThe impact of commonly used alkylating agents on artefactual peptide modification
Iodoacetamide is by far the most commonly used agent for alkylation of cysteine during sample preparation for proteomics. An alternative, 2-chloroacetamide, has been recently suggested to reduce the alkylation of residues other than cysteine, such as the N-terminus, Asp, Glu, Lys, Ser, Thr and Tyr....
ORGANISM(S): Rattus norvegicus (Rat) 
2017-08-16 | PXD007071 | Pride
Post-translational modification Cysteine alkylation Artefact N-terminal alkylation Alkylation 
ProteomicsStructure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex, and the Regulation of Transcription
MedPIC: Crosslinking-MS of 54 subunit pre-initiation complex from yeast. MedPolII: Crosslinking-MS of 33 subunit Mediator + polII complex from yeast.
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2016-08-02 | MSV000080013 | MassIVE
ProteomicsMolecular Architecture of the Yeast Mediator Complex
Cross-linking MS data from the yeast Mediator complex. Cross-linking was performed using either BS3 or 1:1 mix of d0:d12 DSS. Includes unfractionated, SEC enriched, high pH reverse phase fractionated, DDA and inclusion list generated files.
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2015-08-13 | MSV000079237 | MassIVE
UnknownSafety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.
Not available
S-EPMC7723445 | biostudies-literature
UnknownSingle-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials.
Not available
S-EPMC7894131 | biostudies-literature
UnknownPrediction of disability-free survival in healthy older people.
Not available
S-EPMC9213595 | biostudies-literature
UnknownEffect of Aspirin on Disability-free Survival in the Healthy Elderly.
Not available
S-EPMC6426126 | biostudies-literature
UnknownEffect of Aspirin on All-Cause Mortality in the Healthy Elderly.
Not available
S-EPMC6433466 | biostudies-literature
UnknownEffect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly.
Not available
S-EPMC6289056 | biostudies-literature
UnknownComparative effectiveness of immediate antiretroviral therapy versus CD4-based initiation in HIV-positive individuals in high-income countries: observational cohort study.
Not available
S-EPMC4643831 | biostudies-literature
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