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UnknownThe epidemiological signature of influenza B virus and its B/Victoria and B/Yamagata lineages in the 21st century.
Not available
S-EPMC6742362 | biostudies-literature
TranscriptomicsHOXA9 transcriptomic analysis in GBM cell lines (U87MG, U251 and primary GBML18) and in immortalized human astrocytes (hTERT/E6/E7)
Assess gene expression patterns upon HOXA9 ectopic expression in U87MG GBM cell line and hTERT/E6/E7 immortalized human astrocytes, and HOXA9 silencing in U251 and GBML18 GBM cell lines. U87MG and hTERT/E6/E7 were retrovirally-infected with an MSCV control vector (MSCV-Control) or with a construct c...
ORGANISM(S): Homo sapiens 
2015-01-30 | E-GEOD-56517 | biostudies-arrayexpress
UnknownTemporal Patterns of Influenza A and B in Tropical and Temperate Countries: What Are the Lessons for Influenza Vaccination?
Not available
S-EPMC4816507 | biostudies-literature
ProteomicsChronic stress alters the E/I balance of pyramidal neurons in the infralimbic and Prelimbic cortices
The medial prefrontal cortex (mPFC) is a key brain region involved in controlling working memory, executive function, and self-regulatory behaviours, and its malfunction is a hallmark of several neuropsychiatric disorders such as schizophrenia, depression, and post-traumatic stress disorder. One of ...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD047291 | Pride
Infralimbic cortex Chronic stress Prelimbic cortex E/i balance 
ProteomicsChronic stress causes striatal disinhibition mediated by SOM-interneurons
Chronic stress is a major triggering factor for neuropsychiatric disorders including obsessive-compulsive disorder (OCD), a mental health condition characterized by motor stereotypies and striatal overactivation. However, the mechanisms at the cell- and microcircuit-level through which stress trigge...
ORGANISM(S): Mus musculus (Mouse) 
2022-12-13 | PXD031193 | Pride
Striatum Swath-ms Chronic stress 
ProteomicsChronic haloperidol treatment leads to an imbalance of synaptic excitation and inhibition of D1-MSN neurons pointing to a slow remodelling process
Schizophrenia is a chronic mental illness that is among the world’s top twenty causes of years lost to disability according to the global burden of disease 2019 (10.1016/S0140-6736(20)30925-9). Positive symptoms, including hallucinations and delusions in schizophrenia, often improved with convention...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD038471 | Pride
Msn Haloperidol Proteomics 
TranscriptomicsTumor exosome integrins determine organotropic metastasis
Stephen Paget first proposed, in 1889, that organ distribution of metastases is a non-random event, yet metastatic organotropism remains one of the greatest mysteries in cancer biology. Here, we demonstrate that exosomes released by lung-, liver- and brain-tropic tumor cells fuse preferentially with...
ORGANISM(S): Homo sapiens 
2015-06-17 | E-GEOD-68919 | biostudies-arrayexpress
TranscriptomicsPID-1 is a novel factor that operates during 21U RNA biogenesis in Caenorhabditis elegans
Animal germ cells employ small RNA-based mechanisms to recognize and silence DNA that invades their genome. One of these pathways is named the Piwi:piRNA pathway. Biogenesis of piRNAs is poorly understood. In C. elegans, the piRNA (21U-RNA)-binding Argonaute protein PRG-1 is the only known player ac...
ORGANISM(S): Caenorhabditis elegans 
2014-03-17 | E-GEOD-55309 | biostudies-arrayexpress
UnknownKetamine, Etomidate, and Mortality in Emergency Department Intubations.
Not available
S-EPMC12706683 | biostudies-literature
UnknownHydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19.
Not available
S-EPMC7397242 | biostudies-literature
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