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ProteomicsPlk1 Self-Organization and Priming Phosphorylation of HsCYK-4 at the Spindle Midzone
Burkard ME, Maciejowski J, Rodriguez-Bravo V, Repka M, Lowery DM, Clauser KR, Zhang C, Shokat KM, Carr SA, Yaffe MB, Jallepalli PV. PLoS Biology. 2009, 7, 1-16. PMCID: PMC2680336. Tranche_hash:hoZCdxyWctOiblTI0WPcWoNstEY2hXa1nrvH2/zm/8nMEni3uXsGtepf4XeqiDJTGfsP5zOmDl9f4vKwlQuR424g5OoAAAAAAAAJzA==
2013-11-21 | MSV000078497 | MassIVE
UnknownNuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitor.
Not available
S-EPMC3947552 | biostudies-literature
UnknownMps1 Regulates Kinetochore-Microtubule Attachment Stability via the Ska Complex to Ensure Error-Free Chromosome Segregation.
Not available
S-EPMC5477644 | biostudies-literature
ProteomicsChromosomal instability adaptation dependencies confer unique targetable vulnerabilities in therapy refractory lethal prostate cancer
Chromosomal instability (CIN), an ongoing rate of chromosome missegregation during mitosis, is a defining feature of cancer. However, high chromosomal aberrations are detrimental for cell fitness. Here we investigated mechanisms allowing lethal prostate cancer (PCa) to tolerate and survive increasin...
ORGANISM(S): Homo sapiens (Human) 
2023-01-14 | PXD028271 | Pride
Mastl expression Chromosomal instability 
ProteomicsMps1 regulates kinetochore-microtubule attachment stability via the Ska complex to ensure error-free chromosome segregation
Spindle assembly checkpoint (SAC) regulators such as the Mps1 kinase not only delay anaphase onset, but also correct improper chromosome-spindle linkages that would otherwise lead to missegregation and aneuploidy. However, the substrates and mechanisms involved in this pathway of error correction re...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD006135 | Pride
Proteomics Mps1 Chemical genetics Ska complex Spindle assembly checkpoint (sac) Pp2a-b56 
UnknownMechanisms of chromosomal instability (CIN) tolerance in aggressive tumors: surviving the genomic chaos.
Not available
S-EPMC10104937 | biostudies-literature
UnknownIdentification and functional analysis of missense mutations in the lecithin cholesterol acyltransferase gene in a Chilean patient with hypoalphalipoproteinemia.
Not available
S-EPMC6549291 | biostudies-literature
UnknownOvatifolin Purified from <i>Leptocarpha rivularis</i> Induces Cell Death in A375 and A2058 Melanoma Cancer Cells.
Not available
S-EPMC12729485 | biostudies-literature
UnknownCoevolution in human small Heat Shock Protein 1 is promoted by interactions between the Alpha-Crystallin domain and the disordered regions.
Not available
S-EPMC12052118 | biostudies-literature
UnknownGeneration of Prostate Cancer Patient Derived Xenograft Models from Circulating Tumor Cells.
Not available
S-EPMC4692658 | biostudies-literature
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