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Background: Autism spectrum disorder (ASD) is defined as a pervasive developmental disorder which is caused by genetic and environmental risk factors. Besides the core behavioral symptoms, accumulated results indicate children with ASD also share some metabolic abnormalities. Objectives:
2022-03-02 | MTBLS2421 | MetaboLights
Primary human monocytes were isolated and differentiated into moDCs. These moDCs were infected with WT Dengue virus 2 and its attenuated mutants (generated using infectious clone construction with site-directed mutagenesis) to better understand the gene expression changes induced by these different ...
ORGANISM(S): Homo sapiens 
This study investigates the post-vaccination gene expression associated with T cell response and why humoral immunity does not inform cellular responses post-vaccination. The experiment is the transcriptional profiling of peripheral blood mononuclear cells (PBMCs) from 21/27 subjects collected at da...
ORGANISM(S): Homo sapiens 
This study investigates the post-vaccination gene expression associated with protective T cell levels and why it takes two doses to boost an anamnestic response in older adults using the AS01b-adjuvanted recombinant zoster vaccine (RZV, ShingrixTM). The experiment is the transcriptional profiling of...
ORGANISM(S): Homo sapiens 
This study investigates the post-vaccination gene expression associated with T cell response and why humoral immunity does not inform cellular responses post-vaccination. The experiment is the transcriptional profiling of peripheral blood mononuclear cells (PBMCs) from 12 subjects collected at day 0...
ORGANISM(S): Homo sapiens 
HMGB1 were silence in A549 cells using siRNA targeting.These A549 cells were then infected with WT Dengue virus 2 and its attenuated mutants (generated using infectious clone construction with site-directed mutagenesis) to better understand the gene expression changes induced by these different atte...
ORGANISM(S): Homo sapiens 
Primary human monocytes were isolated and differentiated into moDCs. These moDCs were infected with WT Dengue virus 2 and its attenuated mutants (generated using infectious clone construction with site-directed mutagenesis) to better understand the gene expression changes induced by these different ...
ORGANISM(S): Homo sapiens 
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