Neoantigen discovery in pediatric brain tumors is hampered by their low mutational burden and scant tissue availability. We developed a low-input proteogenomic approach combining tumor DNA/RNA sequencing and mass spectrometry proteomics to identify tumor-restricted (neoantigen) peptides arising from...
In order to investigate medulloblastoma biology via its proteome, we undertook a super-SILAC quantitative proteomics survey using 41 clinical tissue samples spanning the 4 genomic subgroups and control cerebellum
