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ProteomicsProteomics analysis of rough endoplasmic reticulum in pancreatic beta cells
Pancreatic beta cells have well-developed endoplasmic reticulum (ER) to accommodate for the massive production and secretion of insulin. ER homeostasis is vital for normal beta cell function. Perturbation of ER homeostasis contributes to beta cell dysfunction in both type 1 and type 2 diabetes. To s...
ORGANISM(S): Mus musculus (Mouse) 
2015-04-15 | PXD001081 | Pride
Insulin biogenesis Pancreatic beta cells Endoplasmic reticulum Gelc-ms/ms 
TranscriptomicsMembrane association and activity of rough endoplasmic reticulum associated RISC requires farnesylated chaperones
Aim and experimental set-up: Sequencing of small RNA from total RNA fractions. The aim of this experiment was to compare profiles of miRNA expression between the following genetic backgrounds: Col-0 (wild type), era1-2 (farnesyl transferase mutant), j2-2/j3-2 + pJ3:J3 (j2/j3 double knockout expres...
ORGANISM(S): Arabidopsis thaliana 
2016-07-31 | E-MTAB-3736 | biostudies-arrayexpress
UnknownProtein translocation across the rough endoplasmic reticulum.
Not available
S-EPMC3552503 | biostudies-literature
GenomicsMembrane association and activity of rough endoplasmic reticulum associated RISC requires farnesylated chaperones
Membrane association and activity of rough endoplasmic reticulum associated RISC requires farnesylated chaperones
PRJEB9861 | ENA
UnknownSelf-Assembled Rough Endoplasmic Reticulum-Like Proto-Organelles.
Not available
S-EPMC6180236 | biostudies-literature
UnknownCalsequestrin accumulation in rough endoplasmic reticulum promotes perinuclear Ca2+ release.
Not available
S-EPMC3351355 | biostudies-literature
UnknownRickettsia parkeri forms extensive, stable contacts with the rough endoplasmic reticulum.
Not available
S-EPMC11706211 | biostudies-literature
ProteomicsImpairment of the rough endoplasmic reticulum/mitochondria compartment in human cardiomyocytes with phospholamban p.Arg14del mutation
Background: The phospholamban (PLN) p.Arg14del mutation belongs to the established causes of dilated cardiomyopathy, with the molecular disease mechanisms incompletely understood. We used human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes, CRISPR/Cas9 gene editing and patient heart s...
ORGANISM(S): Homo sapiens (Human) 
2021-04-12 | PXD020175 | Pride
Phospholamban Proteomics Engineered heart tissue Crispr/cas9 Hipsc Cardiomyopathy 
UnknownGlucocorticoid-dependent Tubulointerstitial Nephritis with IgM-positive Plasma Cells Presenting with Intracellular Crystalline Inclusions within the Rough Endoplasmic Reticulum.
Not available
S-EPMC8545643 | biostudies-literature
TranscriptomicsMicroarray of RNA from calvaria in WT and OASIS-/- (KO) mice
Investigation of whole genome gene expression level changes in OASIS KO calvaria compared to wild-type calvaria. To gain further insight into the potential mechanisms underlying the defective bone formation in OASIS KO mice, we compared the gene expression in calvaria between WT and OASIS KO mice us...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-18062 | biostudies-arrayexpress
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