Sort   by:  
 Page size 
ProteomicsProteomics analysis of rough endoplasmic reticulum in pancreatic beta cells
Pancreatic beta cells have well-developed endoplasmic reticulum (ER) to accommodate for the massive production and secretion of insulin. ER homeostasis is vital for normal beta cell function. Perturbation of ER homeostasis contributes to beta cell dysfunction in both type 1 and type 2 diabetes. To s...
ORGANISM(S): Mus musculus (Mouse) 
2015-04-15 | PXD001081 | Pride
Insulin biogenesis Pancreatic beta cells Endoplasmic reticulum Gelc-ms/ms 
GenomicsMitochondria-Rough-ER Contacts in The Liver Regulate Systemic Lipid Homeostasis
Mitochondria-Rough-ER Contacts in The Liver Regulate Systemic Lipid Homeostasis
PRJNA556401 | ENA
TranscriptomicsMembrane association and activity of rough endoplasmic reticulum associated RISC requires farnesylated chaperones
Aim and experimental set-up: Sequencing of small RNA from total RNA fractions. The aim of this experiment was to compare profiles of miRNA expression between the following genetic backgrounds: Col-0 (wild type), era1-2 (farnesyl transferase mutant), j2-2/j3-2 + pJ3:J3 (j2/j3 double knockout expres...
ORGANISM(S): Arabidopsis thaliana 
2016-07-31 | E-MTAB-3736 | biostudies-arrayexpress
ProteomicsImpairment of the rough endoplasmic reticulum/mitochondria compartment in human cardiomyocytes with phospholamban p.Arg14del mutation
Background: The phospholamban (PLN) p.Arg14del mutation belongs to the established causes of dilated cardiomyopathy, with the molecular disease mechanisms incompletely understood. We used human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes, CRISPR/Cas9 gene editing and patient heart s...
ORGANISM(S): Homo sapiens (Human) 
2021-04-12 | PXD020175 | Pride
Phospholamban Proteomics Engineered heart tissue Crispr/cas9 Hipsc Cardiomyopathy 
UnknownRibosome-free terminals of rough ER allow formation of STIM1 puncta and segregation of STIM1 from IP(3) receptors.
Not available
S-EPMC2887489 | biostudies-literature
TranscriptomicsMitochondria-Rough-ER Contacts in The Liver Regulate Systemic Lipid Homeostasis
Contacts between organelles create microdomains that play major roles in regulating key intracellular activities and signaling pathways, but whether they also regulate systemic functions remains unknown. Here, we report the ultrastructural organization and dynamics of the inter-organellar contact es...
ORGANISM(S): Mus musculus 
2021-03-15 | GSE134777 | GEO
UnknownCalsequestrin accumulation in rough endoplasmic reticulum promotes perinuclear Ca2+ release.
Not available
S-EPMC3351355 | biostudies-literature
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of Wild Type and fl4 mutant Transcriptomes
Analysis of gene expression level. The hypothesis tested in the present study was that fl4 mutant influence the ER stress pathway. Results provide important information of the gene expression level regulation of different ER stress pathways and apoptosis Endosperm mRNA profiles of 19DAP wild type (...
ORGANISM(S): Zea mays 
2014-01-18 | E-GEOD-54184 | biostudies-arrayexpress
UnknownProteomics analysis of rough endoplasmic reticulum in pancreatic beta cells.
Not available
S-EPMC4489703 | biostudies-literature
UnknownRickettsia parkeri forms extensive, stable contacts with the rough endoplasmic reticulum.
Not available
S-EPMC11706211 | biostudies-literature
Sort   by:  
 Page size