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ProteomicsThe melanoma cell line RPMI-7951 adhesome in long-term culture and its comparison to the adhesome upon integrin αV knockdown
Integrins are involved in the metastatic cascade and have been found to be responsible for intrinsic and acquired therapy resistance. Therefore, targeting integrins, or more specifically the signal transduction via integrin adhesion complexes (IACs), is a promising therapeutic opportunity to reduce ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD064756 | Pride
ProteomicsThe composition of reticular adhesions in RPMI-7951 and MDA-MB-435S melanoma cell lines and its comparison with the reticular adhesion composition following talin2 or KANK2 knockdown
Integrins bind extracellular matrix proteins and, when clustered, form integrin adhesion complexes (IACs) that connect to and regulate the cytoskeleton, shaping normal and tumour cell behaviour. In addition to well-known nascent adhesions, focal adhesions (FAs), fibrillar adhesions (FBs), and hemide...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD071922 | Pride
Reticular adhesions Kank2 Matrisome Adhesome Melanoma Rpmi-7951 cells Integrin alphavbeta5 Talin2 Mda-mb-435s cells 
TranscriptomicsSix melanoma cancer cell lines transcriptomics (metastatic and primary)
We report the six metastatic (RPMI-7951,SK-MEL-3,SH-4) and primary (A375,G-361,SK-MEL-1) melanoma cancer cells transcriptomics.
ORGANISM(S): Homo sapiens 
2021-03-14 | GSE162270 | GEO
UnknownTwo New Steroidal Monoglycosides, Anthenosides A₁ and A₂, and Revision of the Structure of Known Anthenoside A with Unusual Monosaccharide Residue from the Starfish Anthenea aspera.
Not available
S-EPMC6102596 | biostudies-literature
UnknownInhibiting IL11RA to mitigate hepatic metastasis in skin cutaneous melanoma: Comprehensive insights from in vitro and in vivo investigations.
Not available
S-EPMC10928329 | biostudies-literature
UnknownVitamin D Enhances Anticancer Properties of Cediranib, a VEGFR Inhibitor, by Modulation of VEGFR2 Expression in Melanoma Cells.
Not available
S-EPMC8740239 | biostudies-literature
UnknownNew Triterpene Glycosides from the Far Eastern Starfish Solaster pacificus and Their Biological Activity.
Not available
S-EPMC8001898 | biostudies-literature
UnknownA Reconstructed Human Melanoma-in-Skin Model to Study Immune Modulatory and Angiogenic Mechanisms Facilitating Initial Melanoma Growth and Invasion.
Not available
S-EPMC10216824 | biostudies-literature
UnknownPhytochemical Composition of Commiphora Oleogum Resins and Their Cytotoxicity against Skin Cancer Cells.
Not available
S-EPMC9229828 | biostudies-literature
UnknownFour New Sulfated Polar Steroids from the Far Eastern Starfish Leptasterias ochotensis: Structures and Activities.
Not available
S-EPMC4515625 | biostudies-literature
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