We performed genome-wide expression profiling of cells infected with control or RPS14 shRNAs. Experiment Overall Design: The purpose of the dataset is to profile analyze the effect of silencing RPS14
5q- syndrome is a somatic ribosomopathy linked to the monoallelic deletion of the RPS14 gene and characterized by a proeminent erythroid phenotype. The mechanism of anemia involves an impaired differentiation and increased apoptosis of erythroblasts. We have analyzed total cell extracts from UT7 cel...