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UnknownLow-order assemblies drive oncogenic RTK fusion signaling without condensation.
Not available
S-EPMC12715544 | biostudies-literature
ProteomicsProbing downstream effects of ALK and ROS1 fusion oncogenes in Glioma using proteomics
To identify targets of aberrantly expressed RTK-fusion oncogenes, serine/threonine and tyrosine phosphorylation signatures in transgenic cells lines expressing different RTK-fusion oncogenes were compared with their respective kinasedead mutant counterparts. Comparing the differentially phosphorylat...
ORGANISM(S): Homo sapiens (Human) 
2026-01-22 | PXD059984 | Pride
Alk Ap-ms Ros1 Immortalized normal human astrocytes Phosphoprotoemics Rtk-fusion oncoproteins 
UnknownDifferential Subcellular Localization Regulates Oncogenic Signaling by ROS1 Kinase Fusion Proteins.
Not available
S-EPMC6359944 | biostudies-literature
UnknownKinase-mediated RAS signaling via membraneless cytoplasmic protein granules.
Not available
S-EPMC8127962 | biostudies-literature
UnknownProfiling Receptor Tyrosine Kinase Fusions in Chinese Breast Cancers.
Not available
S-EPMC8506003 | biostudies-literature
Unknown<i>TG-IGF1R</i>: A Novel Receptor Tyrosine Kinase Fusion Oncogene in Pediatric Thyroid Cancer.
Not available
S-EPMC11958905 | biostudies-literature
TranscriptomicsDual regulation of Fbw7 function and oncogenic transformation by Usp28
Fbw7, the substrate recognition subunit of SCF(Fbw7) ubiquitin ligase, mediates turnover of multiple proto-oncoproteins and promotes its own degradation. Fbw7-mediated substrate degradation is antagonized by the Usp28 deubiquitinase. We now show, using knockout mice, that Usp28 preferentially deubiq...
ORGANISM(S): Mus musculus 
2015-05-01 | E-GEOD-59354 | biostudies-arrayexpress
TranscriptomicsWild-Type Nras Lacks Tumor Suppressor Activity and Nras Oncogene Dosage Strongly Modulates Hematopoietic Transformation
Contemporary treatment of pediatric acute myeloid leukemia (AML) requires the assignment of patients to specific risk groups. To explore whether expression profiling of leukemic blasts could accurately distinguish between the known risk groups of AML, we analyzed 130 pediatric and 20 adult AML diagn...
ORGANISM(S): Homo sapiens 
2013-07-02 | E-GEOD-43176 | biostudies-arrayexpress
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