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Analysis of serum starved prelamin A-accumulating hMSCs at gene expression level. The hypothesis tested in the present study was that prelamin A accumulation induces the dysregulation of genes that are essensial for cell survival under a stress condition such as serum starvation. The results provide...
ORGANISM(S): Homo sapiens 
Chronic nutrient excess leads to metabolic disorders and insulin resistance. Activation of stress-responsive pathways via Nrf2 activation contributes to energy metabolism regulation. Here, inducible activation of Nrf2 in mice and transgenesis of the Nrf2 target, NQO1, conferred protection from diet-...
2024-05-23 | MTBLS2085 | MetaboLights
We have characterised the product of a novel N terminal deletion of Lbr gene.
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-09-10 | PXD024111 | Pride
Human Pak3-T421E cDNA with a flag tag was transfected into HEK293 cells using Lipofectomine 2000, After 72 hrs of incubation, PAK3 interactors were pulldwon with FLAG antibody. A sample without PAK3 overexpression was used as a negative control. Changes in PAK3 interactions between basal and starvat...
ORGANISM(S): Homo sapiens (Human) 
2023-05-16 | PXD041986 | Pride
In this project, we have studied the role of Chd8 in Xist regulation and XCI initiation by means of Chd8 Knock-Downs (KD) and Knock-Out (KO).
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-09-10 | PXD024155 | Pride
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