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The presence of Rv2577 in the cell wall and soluble fractions was determined by nano-HPLC- MS/MS
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
2021-09-09 | PXD019769 | Pride
This study uses RNA-seq to quantitatively compare the gene expression profiles of THP-1 macrophages infected with the wild-type (WT), mgdE-deleted (ΔmgdE), and mmpE-deleted (ΔmmpE) strains of Mycobacterium bovis BCG, in order to investigate the roles of two conserved nucleomodulins, MgdE (Rv1075c) a...
ORGANISM(S): Homo sapiens 
2025-12-05 | GSE312039 | GEO
Nucleomodulins are bacterial effectors that target host cell nuclei and play crucial roles as virulence factors in mycobacterial pathogenesis. Mycobacterium tuberculosis, the causative agent of tuberculosis, presents a significant global health challenge; however, the mechanisms of nucleomodulins in...
ORGANISM(S): Homo sapiens 
2025-12-12 | GSE312934 | GEO
Differential transcriptional effects of mycobacterial nucleomodulins MgdE and MmpE in THP-1 macrophages
Mycobacterial Metallophosphatase MmpE Functions as a Nucleomodulin to Regulate Host Gene Expression and Promote Intracellular Survival
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