S100a9 - OmicsDI

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Unknown (963)
Transcriptomics (287)
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Organisms

Mus musculus (158)
Homo sapiens (132)
Schizophyllum commune H4-8 (38)
Mycobacterium tuberculosis SP7 (38)
Oryza sativa Japonica Group (38)
Crotalus durissus terrificus (38)
Eriocheir sinensis (38)
Candidatus Endoriftia persephonae (38)
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Mycobacterium tuberculosis SP13 (38)
Cotesia typhae (38)
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Cepaea nemoralis (38)
Enterobacter ludwigii (38)
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Organisms

Homo sapiens (67)
Mus musculus (61)
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Mus (1)
Macaca mulatta (1)
feces metagenome (1)
mouse gut metagenome (1)
Bos taurus (1)
unidentified (1)

Repository

biostudies-arrayexpress (181)
ENA (163)
geo (135)
pride (38)
iProX (12)
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Tissue

Cell culture (5)
Blood plasma (4)
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Neutrophil (3)
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Ileum (2)
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Blood platelet (2)
Macrophage (2)
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Salivary gland (1)
Bone marrow (1)

Disease

Normal (2)
Inflammatory bowel disease (2)
Cardiovascular system disease (2)
Crohn's disease (2)
Ulcerative colitis (2)
Breast cancer (2)
Salivary gland disease (1)
Alcohol-associated liver disease (1)
Central retinal vein occlusion (1)
Gastrointestinal system disease (1)
Acute myocardial infarction (1)
Cerebrovascular disease (1)
Lewy body dementia (1)
Type 1 diabetes mellitus (1)
Brain glioblastoma multiforme (1)
Pancreatic ductal adenocarcinoma (1)
Pancreatic cancer (1)
Myocardial ischemia (1)

Technology Type

Mass Spectrometry (38)
Shotgun proteomics (18)
Bottom-up proteomics (10)
Data-dependent acquisition (5)
Gel-based experiment (4)
Mass spectrometry (3)
SWATH MS (3)
Data-independent acquisition (3)
MSE (1)
DiaPASEF (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (10)
Illumina HiSeq 2500 (7)
Illumina NovaSeq X (5)
NextSeq 2000 (5)
Illumina HiSeq 4000 (5)
Illumina HiSeq 2000 (4)
N/A (3)
Q Exactive (3)
BeadBug Benchtop homogenizer (2)
NextSeq 500 (2)
Liquid Chromatography MS - negative - reverse phase (2)
NextSeq 550 (Illumina). (1)
Molecular Biology laboratory (1)
Mammalian cell culture laboratory (1)
FastPrep-24 5G bead beater, Qubit Fluorometer (1)
12 well TC-treated plate, LETs buffer, dry ice (1)
454 GS FLX Titanium (1)
ScanArray [PerkinElmer] (1)
NA (1)
NextSeq 550 (1)
Q Exactive HF-X (1)
Liquid Chromatography MS - alternating - reverse phase (1)
Liquid Chromatography MS - positive - reverse phase (1)

Publication Date

2025 (40)
2023 (30)
2026 (29)
2024 (28)
2013 (27)
2022 (23)
2020 (22)
2014 (21)
2008 (21)
2015 (20)
2012 (18)
2016 (15)
2011 (14)
2021 (14)
2010 (12)
2007 (8)
2019 (7)
2017 (7)
2009 (7)
2018 (4)
2005 (3)
2006 (2)

CHEBI ID

CHEBI:63999 (1)
CHEBI:90995 (1)
CHEBI:34159 (1)
CHEBI:184926 (1)
CHEBI:84549 (1)
CHEBI:170340 (1)
CHEBI:197368 (1)
CHEBI:197369 (1)
CHEBI:185779 (1)
CHEBI:172762 (1)
CHEBI:135821 (1)
CHEBI:180757 (1)
CHEBI:27423 (1)
CHEBI:159174 (1)
CHEBI:16214 (1)
CHEBI:160004 (1)
CHEBI:173286 (1)
CHEBI:185983 (1)
CHEBI:158820 (1)
CHEBI:196609 (1)
CHEBI:164479 (1)
CHEBI:158854 (1)
CHEBI:165804 (1)
CHEBI:163500 (1)
CHEBI:20096 (1)
CHEBI:174796 (1)
CHEBI:173157 (1)
CHEBI:196525 (1)
CHEBI:71052 (1)
CHEBI:169897 (1)

Metabolite Name

LXA4 (1)
15-deoxy-12-14-PGD2 (1)
12-HETrE (1)
15-deoxy-12-14-PGJ2 (1)
9-10-DiHOME (1)
12-13-DiHOME (1)
(2E)-N-[4-(acetylamino)phenyl]-3-phenylprop-2-enamide (1)
C27H40O11 (1)
FT-sulfoxide; C12H18F7NO5S2 (1)
Glu-CA (1)
[3-Methyl-1-[3-methyl-1-oxo-1-(2,3,4,5,6-pentahydroxyhexoxy)pentan-2-yl]oxy-1-oxobutan-2-yl] 2-hydroxy-3-methylpentanoate (1)
6-(2-hydroxyethyl)-6,6a-dihydroisoindolo[2,1-a]quinazoline-5,11-dione (1)
3-Nitropropionic acid (1)
Mls002702983 (1)
C13H23NO7 (1)
11-Methyl-2,7-bis(methylene)-6,12-dioxo-5,14-dioxatricyclo[9.2.1.0~4,8~]tetradec-1(13)-en-9-yl methacrylate (1)
Biflorin (Capraria) (1)
Trimethyl(2-{[3-[octadeca-9,12-dienoyloxy]-2-(octadecanoyloxy)propyl phosphonato]oxy}ethyl)azanium (1)
Austrobuxusin I (1)
Mls001140705 (1)
Sr 2640 (1)
Haploside C (1)
Trp-CA (1)
N-[(1E)-2-(4-hydroxy-3-methoxyphenyl)-1-azavinyl]-2-[(3,5-dioxo(2H,4H-1,2,4-tr iazin-6-yl))amino]acetamide (1)
(2-iminochromen-3-yl)-N-(4-methylphenyl)carboxamide (1)
Gamma-Homolinolenic acid (1)
N-O-Fluorophenylglycine (1)
2H-benzo[d]1,3-dioxolan-5-yl-N-(4,5-dimethyl(1,3-thiazol-2-yl))carboxamide (1)
2-methoxyethyl 4-(3-bromo-5-ethoxy-4-hydroxyphenyl)-2-methyl-5-oxo-7-phenyl-1, 4,6,7,8-pentahydroquinoline-3-carboxylate (1)
4-O-Methylphloroacetophenone (1)

First Public Date

2024 (31)
2025 (28)
2026 (20)
2023 (16)
2021 (15)
2020 (15)
2014 (14)
2022 (13)
2018 (4)
2019 (2)
2017 (2)
2015 (2)
2013 (1)

Modelling Approach

Computational model (1)

Lab affiliation

King's College London, British Heart Foundation Centre, School of Cardiovascular Medicine and Sciences, London, UK (2)
Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel (2)
Faculty of Health Sciences, University of Macau, Macau, China (2)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands and Netherlands Proteomics Center, Utrecht, The Netherlands (1)
King's British Heart Foundation Centre, King's College London, London, United Kingdom (1)
Professor at Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India (1)
Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu, China, 610052 (1)
Dr Ainhoa Mielgo, Tumour Microenvironment Lab, Department of Molecular and Clincial Cancer Medicine, University of Liverpool (1)
Institute of Medical Biochemistry, Protein Core Facility, Medical University of Innsbruck, 6020 Innsbruck, Austria (1)
Baker Heart and Diabetes Institute, Aus (1)
Laboratory of Biopolymers Structure, Intercollegiate Faculty of Biotechnology of University of Gdańsk and Medical University of Gdańsk, Poland (1)
Consultant Medical oncology (1)
Keck MS & Proteomics Resource at Yale School of Medicine (1)
HZAU (1)
Department of Plasma Proteins, Sanquin-AMC Landsteiner Laboratory, Amsterdam, The Netherlands (1)
Department of Cell Physiology and Metabolism, Faculty of medicine, University of Geneva (1)
Institute of Cellular Biology and Pathology "N. Simionescu", Proteomics Department, Bucharest, Romania (1)
Institute of Biomedical Chemistry, 119121 Moscow, 10 Pogodinskaya str., bld. 8, Russian Federation; tel.: +7 495 246 16 41; web: www.ibmc.msk.ru (1)
University of Geneva, Faculty of Medicine, Department of Cell physiology and Metabolism (1)
1. INSERM U1287, Université Paris-Saclay, Gustave Roussy Cancer Center, Villejuif, France 2. Université Paris-Saclay, Faculté de Médecine, Le Kremlin-Bicêtre, France (1)
Bioanalytical Research Labs, Department of Biosciences, University of Salzburg (1)
Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, Bochum, Germany (1)
Vanderbilt University, Mass Spectrometry Research Center (1)
Institute of Cellular Biology and Pathology (1)
The University of Hong Kong (1)
Molecular Proteomics, Baker Heart Inst., Australia (1)
College of Biology, Hunan University, China (1)
Biomolecular characterization unit, Center for Sustainable Resource Science, RIKEN (1)
Department of Biochemistry and Molecular Biology, University of Calgary, Alberta, Canada; Department of Physiology and Pharmacology, University of Calgary, Alberta, Canada; The Hotchkiss Brain Institute, University of Calgary, Alberta, Canada; McCaig Institute for Bone and Joint Health, University of Calgary, Alberta, Canada (1)
Boston College, Chemistry (1)

IsPrivate

False (1)

Submitter Keywords

FAIR-AIML (1)

Classification

bacteria (1)

Modification

Heavy form - site K (1)
Heavy form (1)
Medium form - site K (1)
Medium form - site N-term (1)

Study type

Transcription profiling by array (118)
RNA-seq of coding RNA (25)
Methylation profiling by high throughput sequencing (10)
RNA-seq of coding RNA from single cells (5)
ChIP-seq (4)
Methylation profiling by array (4)
Transcription profiling by RT-PCR (3)
DNA-seq (2)
RNA-seq of non coding RNA (2)
Transcription profiling by SAGE (1)
Unknown experiment type (1)
ChIP-chip by tiling array (1)
Animal - High-throughput sequencing (1)
Comparative genomic hybridization by array (1)
Other (1)
Proteomic profiling by array (1)
RNA-seq of total RNA (1)

Release Date

2022 (134)
2021 (115)
2025 (113)
2023 (112)
2024 (104)
2020 (82)
2015 (51)
2014 (51)
2019 (47)
2013 (46)
2018 (45)
2016 (43)
2017 (30)
2012 (30)
2026 (28)
2011 (27)
2010 (26)
2008 (24)
2009 (19)
2007 (8)
2006 (5)
2005 (4)

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Fecal detection of calprotectin subunits links IBD activity with chronicity of intestinal inflammation.

Quantification of the human S100A8/S100A9 tetrameric protein complex in stool, referred to as fecal calprotectin, is an extensively validated biomarker supporting the diagnosis and management of gastrointestinal diseases1,2. The quaternary protein structures (called configuration here) of S100A8 and...

ORGANISM(S): Homo sapiens (Human)

2025-12-18 | PXD068250 | Pride

Proteomic profie of S100A9-immunoprecipitation

proteomic profie of S100A9-immunoprecipitation in human amnion fibroblasts

ORGANISM(S): Homo Sapiens

PXD054794 |

RNA sequencing of MOLM-13 and KG-1a cell lines after inhibition of S100A9 and BCL2

The aim is investigate the alterations in the transcriptome after combined inhibition of S100A9 and BCL2 in AML cell lines.

ORGANISM(S): Homo sapiens

2023-12-01 | E-MTAB-13095 | biostudies-arrayexpress

Short-term blockade of pro-inflammatory alarmin S100A9 fa-vorably modulates left ventricle proteome and related signaling pathways involved in post – myocardial infarction recovery

Prognosis after myocardial infarction (MI) varies greatly depending of the extent of damaged area and the management of biological processes during recovery. Reportedly, the inhibition of the pro-inflammatory S100A9 reduces myocardial damage after MI. We hypothesize that S100A9 blockade induces chan...

ORGANISM(S): Mus musculus (Mouse)

2022-05-19 | PXD033683 | Pride

Hypertrophy Apoptosis Cardiac repair S100a9 Myocardial infarction

Biological effects of recombinant S100A8, recombinant S100A9, and recombinant S100A8/S100A9 on human renal tubular epithelial cells (HK-2)

PRJNA1104534 | ENA

Mitochondrial Proteomics Uncovers Myeloid S100A9 Deficiency Promotes Liver Injury and Fibrosis Regression via Mitochondrial Metabolic Reprogramming of Macrophages

Macrophage-mediated inflammation has been implicated in the pathogenesis of liver fibrosis. Metabolic reprogramming involves in the transition of macrophages from a pro-inflammatory M1-phenotype toward an anti-inflammatory M2-phenotype. S100A9 is highly expressed in activated macrophages and promote...

ORGANISM(S): Mus Musculus

2025-11-03 | PXD070260 |

Neutrophil S100A9 supports M2 macrophage niche formation in granulomas

PRJNA684150 | ENA

The alarmin S100A9 hampers retroviral infection by limiting reverse transcription

PRJNA727578 | ENA

Platelet derived S100A9 contributes to Endotheliopathy in Alcohol-Associated Hepatitis

Alcohol-associated liver disease (ALD) is a growing global health concern, with alcohol-associated hepatitis (AH) leading to the highest morbidity and mortality. Available therapies are limited and often inadequate. Platelets contribute in a variety of ways to the pathogenesis of liver diseases, but...

ORGANISM(S): Homo sapiens (Human)

2026-06-26 | PXD078511 | Pride

Endothelial cells Alcohol-associated hepatitis Endotheliopathy Platelets

Platelet-derived S100A9 contributes to Endotheliopathy in Alcohol-Associated Hepatitis

PRJNA1471019 | ENA

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