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In this study, we used Saccharomyces cerevisiae to investigate the effects of GRX deletion on yeast chronological life span (CLS). Deletion of Grx1 or Grx2 shortened yeast CLS. Quantitative proteomics revealed that GRX deletion increased cellular ROS levels to activate Ras/PKA signal pathway. Our re...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-02-25 | PXD009699 | Pride
Expression profiles of 110 the central metabolism-related enzymes were obtained by the selected reaction monitoring (SRM) assay methods using LC-MS/MS from the wild type (BY4742), a GCR2 gene deletion strain, and 29 single-gene deletion strains lacking enzyme genes responsible for central carbon met...
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast) 
Multi-omics Elucidation of Resource Allocation for Enhanced Ethanol Production via Precise Glucose Control in Anaerobic Saccharomyces cerevisiae Fermentation
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-12-08 | PXD068901 | Pride
IP-MS detection of proteins pulled down by Glc7-FLAG by mass spectrometry
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-10-24 | PXD036005 | Pride
IP-MS detection of proteins pulled down by Ino80-FLAG by mass spectrometry
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-02-07 | PXD035908 | Pride
IP-MS detection of proteins pulled down by Rpd3-FLAG by mass spectrometry
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-02-07 | PXD035910 | Pride
Lactulose-derived oligosaccharides (OsLu) are prebiotic galactooligosaccharides (GOS) known to be beneficial for human health. Many of these carbohydrates are reported to have immunomodulatory properties; however the molecular mechanism is unclear. OsLu produced by enzymatic synthesis can be purifie...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-12-11 | PXD010495 | Pride
The Pleiotropic Drug Resistance (PDR) network is central to the drug response in fungi, and its overactivation is associated with drug resistance. However, gene regulation of the PDR network is not well understood. Here, we established a method to identify proteins that bind promoter of the PDR5 mul...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-02-22 | PXD028798 | Pride
S. cerevisiae BY4741 strain was treated with 1mM NaNO2 in SD + Lys, Arg with pH 4.0. Whole cell extracts were subjected to SDS-PAGE and Flamingo staining. Gels were treated wit trypsin and then extracted peptides were analyzed by LC/MS/MS.
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast) 

This study employs yeast as a model system to thoroughly investigate the differences in regulatory mechanisms under various nutrient limitation conditions, utilizing a systems biology approach integrated with techniques such as multi-omics analysis.To obtain a comprehensive quantitative landscap...

2026-05-24 | MTBLS14573 | MetaboLights
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