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TranscriptomicsTranscription profiling of mice overexpressing spermidine/spermine N1-acetyltransferase (SSAT)
Type 2 diabetes is a complex disorder due to defects in insulin secretion and insulin action. Therefore, we investigated mice overexpressing spermidine/spermine N1-acetyltransferase (SSAT) have reduced amount of white adipose tissue, high basal metabolic rate, improved glucose tolerance, high insul...
ORGANISM(S): Mus musculus 
2007-04-25 | E-MEXP-165 | biostudies-arrayexpress
TranscriptomicsResponse of human lymphoblastoid cells to HZE (iron ions) or gamma-rays
Transcriptional profiling of human lymphoblastoid TK6 cells comparing mock irradiated cells with cells exposed 24 hours previously to 1.67 Gy HZE (1 GeV/amu iron ions accelerated at the NASA Space Research Laboratory (NSRL) of Brookhaven National Laboratory) or 2.5 Gy 137Cs gamma rays. TK6 cells wer...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-16518 | biostudies-arrayexpress
TranscriptomicsMammary gene expression profile of goats receiving high or low forage diets supplemented or not with lipids
Animal nutrition considerably affects milk composition that influences its nutritional quality. Milk component synthesis and secretion by the mammary gland involve the expression of a large number of genes whose nutritional regulation remains poorly defined. In this study, 16 lactating goats receive...
ORGANISM(S): Capra hircus 
2009-11-29 | E-GEOD-11592 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human prostate cancer primary cultures
The histopathological and molecular heterogeneity of prostate cancer and the limited availability of human tumor tissue make unraveling the mechanisms of prostate carcinogenesis a challenging task. Our goal was to develop an ex vivo model that could be reliably utilized to define a prognostic signat...
ORGANISM(S): Homo sapiens 
2007-06-30 | E-GEOD-3868 | biostudies-arrayexpress
TranscriptomicsResponse of human lymphoblastoid cells to HZE (iron ions), gamma-rays, and activated medium
This SuperSeries is composed of the following subset Series: GSE16518: Response of human lymphoblastoid cells to HZE (iron ions) or gamma-rays GSE16519: Response of human lymphoblastoid cells to activated medium Refer to individual Series
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-16525 | biostudies-arrayexpress
TranscriptomicsMicroarray profiles of radiation response in the NCI60 cell lines
The 60 cell lines of the NCI Anti-Cancer Drug Screen (NCI60) constitute the most extensively characterized in vitro cancer cell model, and have been tested for sensitivity to over 100,000 potential chemotherapy agents. We have used the NCI60 cell lines and three additional lymphoblast lines to deve...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-7505 | biostudies-arrayexpress
TranscriptomicsRNAi knock down of VCP in human HeLa cells
Study of the effects of the VCP knockdown. VCP (p97, yeast cdc48) is a hexameric AAA ATPase involved in various cellular functions including degradation of proteins by the ubiquitin-proteasome system. We examine the consequences of the reduction of VCP levels after RNAi of VCP in HeLa cells. We find...
ORGANISM(S): Homo sapiens 
2006-08-23 | E-MEXP-817 | biostudies-arrayexpress
no omics definedTranscription profiling of human ileal epithilium in patients suffering from Crohn's disease
Identification of significant regulated genes of the ileal epithelium in patients suffering from Crohn disease (normal vs. activ and non activ CD).
ORGANISM(S): Homo sapiens 
2009-02-27 | E-MEXP-1225 | biostudies-arrayexpress
TranscriptomicsWhole Genome Analysis of the Heat Stress Response in Commercial Baker's Yeast (Saccharomyces cerevisiae) with Comparative Statistical Approaches
Environmental conditions are quite effective during propagation and industrial application of Baker’s yeast (Saccharomyces cerevisiae). The change of temperature is one of the most important conditions which affects the dough-leaving capacity of yeast cells. Accordingly, heat changes play an essential...
ORGANISM(S): Saccharomyces cerevisiae S288c 
2017-01-30 | E-MTAB-3459 | biostudies-arrayexpress
TranscriptomicsBacillus cereus strain 31673
Comparative Genomic Hybridization. Analysis of genomic content of closely related Bacillus species. Refer to individual records for strain information. Refer to platform and individual sample records for experimental protocols.
ORGANISM(S): Bacillus anthracis str. Ames 
2010-06-05 | E-GEOD-568 | biostudies-arrayexpress
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