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TranscriptomicsS-adenosylmethionine (SAM) changes DNA methylation patterns in prostate cancer cells
Genome-wide DNA methylation profiling of human PC3 invasive prostate cancer cell line treated with vehicle control (SAH, S-adenosylhomocysteine) and with SAM (S-adenosylmethionine) as well as of untreated human LNCaP non-invasive prostate cancer cell line. The Illumina Infinium 450k Human DNA Methyl...
ORGANISM(S): Homo sapiens 
2015-03-01 | E-GEOD-62053 | biostudies-arrayexpress
ProteomicsProteomic and phosphoproteomic profiling in heart failure with preserved ejection fraction (HFpEF)
Although the prevalence of heart failure with preserved ejection fraction (HFpEF) is increasing, evidence-based therapies for HFpEF are rare, likely due to an incomplete understanding of this disease. This study sought to identify the cardiac-specific features of protein and phosphoprotein in a muri...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-15 | PXD033501 | Pride
Metabolism Proteomics Sirt3 Mitochondria Hfpef Titin Phosphoproteomics 
MetabolomicsHealth outcomes of fruit juice and fruity beverage: a comparative analysis of gut microbiota and metabolomics in rats (Metabolomics assay)

BACKGROUND: Evidence on the relationship between food processing and health outcomes has been increasing steadily. Under this context, ultra-processing food, such as sugar-sweetened fruity beverages (SS-FB), is associated with a higher risk of metabolic syndrome. However, whether...

2022-08-24 | MTBLS3943 | MetaboLights
UnknownDiscovery of novel bacterial queuine salvage enzymes and pathways in human pathogens.
Not available
S-EPMC6754566 | biostudies-literature
TranscriptomicsHDAC Inhibitors induce tumor cell-selective pro-apoptotic transcriptional responses.
The identification of recurrent somatic mutations in genes encoding epigenetic enzymes, coupled with biochemical studies demonstrating aberrant recruitment of epigenetic enzymes such as histone deacetylases (HDACs) and histone methyltransferases (HMTs) to promoter regions through association with on...
ORGANISM(S): Homo sapiens 
2013-04-22 | E-GEOD-43010 | biostudies-arrayexpress
MetabolomicsMechanisms of hepatic steatosis in chickens: integrated analysis of the host genome, molecular phenomes and gut microbiome

Hepatic steatosis is the initial manifestation of abnormal liver functions and often leads to liver diseases such as non-alcoholic fatty liver disease in humans and fatty liver syndrome in animals. In this study, we conducted a comprehensive analysis of a large chicken population consisting of 70...

2023-07-24 | MTBLS7808 | MetaboLights
ProteomicsMeant_RSK_BioID_2019
This dataset consists of 33 raw MS files and associated peak lists and result files, acquired on an Orbitrap Fusion Tribrid mass spectrometer operated in Data Dependent Acquisition mode. The files are associated with a manuscript submitted for publication by Antoine Meant et al. titled: RSK promote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-02-07 | MSV000083414 | MassIVE
TranscriptomicsCorrelation of transcriptomic responses and metal bioaccumulation in Mytilus edulis L. reveals early indicators of stress
Marine biomonitoring programs in the U.S. and Europe have historically relied on monitoring tissue concentrations of bivalves to monitor contaminant levels and ecosystem health. By integrating M-bM-^@M-^Xomic methods with these tissue residue approaches we can uncover mechanistic insight to help li...
ORGANISM(S): Mytilus edulis 
2014-06-20 | E-GEOD-58649 | biostudies-arrayexpress
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