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GenomicsVitamin C induces Tet-dependent DNA demethylation in ES cells to promote a blastocyst-like methylome [MeDIP-Seq]
DNA methylation is a heritable epigenetic modification involved in gene silencing, imprinting, and the suppression of retrotransposons. Global DNA demethylation occurs in the early embryo and the germline and may be mediated by Tet (ten-eleven-translocation) enzymes, which convert 5-methylcytosine (...
ORGANISM(S): Mus musculus 
2013-06-30 | E-GEOD-46402 | biostudies-arrayexpress
TranscriptomicsVitamin C induces Tet-dependent DNA demethylation in ES cells to promote a blastocyst-like methylome [Affymetrix]
DNA methylation is a heritable epigenetic modification involved in gene silencing, imprinting, and the suppression of retrotransposons. Global DNA demethylation occurs in the early embryo and the germline and may be mediated by Tet (ten-eleven-translocation) enzymes, which convert 5-methylcytosine (...
ORGANISM(S): Mus musculus 
2013-06-30 | E-GEOD-46319 | biostudies-arrayexpress
UnknownPredicting poverty. Data mining approaches to the health and demographic surveillance system in Cuatro Santos, Nicaragua.
Not available
S-EPMC6819397 | biostudies-literature
UnknownRepertoire of Computationally Designed Peroxygenases for Enantiodivergent C-H Oxyfunctionalization Reactions.
Not available
S-EPMC9936548 | biostudies-literature
UnknownTemperature-induced formation of Pd nanoparticles in heterogeneous nanobiohybrids: application in C-H activation catalysis.
Not available
S-EPMC9846520 | biostudies-literature
ProteomicsThe PII protein-protein interaction network in Azospirillum brasilense reveals a novel role of PII in the control of c-di-GMP homeostasis
The PII family comprises a group of widely distributed signal transduction proteins ubiquitous present in prokaryotes and in the chloroplast of plants. The PII proteins sense the levels of key metabolites ATP, ADP and 2-oxoglutarate which affect the PII structure and the ability of PII to interact w...
ORGANISM(S): Azospirillum brasilense Sp245 
2020-10-23 | PXD018530 | Pride
C-di-gmp Protein interaction Motility Pii protein Metabolic regulation 
ProteomicsProtein-related hydrophobicity differences among strains belonging to Candidozyma auris (Candida auris) clades.
The goal of this work was to compare strains from the C. auris clades by assessing some virulence factor, such as cell surface hydrophobicity and biofilm formation. Our results indicate key phenotypic differences between strains assigned to different C. auris clades, which were validated by the use ...
ORGANISM(S): Candidozyma aff. auris 
2026-03-19 | PXD074750 | Pride
C. auris Biofilms Hydrophobicity Mass spectrometry Proteins 
ProteomicsCellular and molecular responses of Cryptococcus to brilacidin (MMV1634402) and KIN1400 (MMV019724)
Cryptococcosis is a systemic mycosis caused by Cryptococcus neoformans and C. deuterogattii. Available therapeu-tic options are limited and face several challenges, including high toxicity, the emergence of resistant strains, high costs, and restrict-ed distribution. In this study, we evaluated the ...
ORGANISM(S): Cryptococcus neoformans H99-YPD_1 
2026-09-07 | PXD070309 | Pride
Cryptococcus neoformans Proteomics. Biofilm Cryptococcus deuterogattii Cryptococcosis Antifungal drugs syner-gism Antifungal activity 
UnknownAn investigator-blinded, 24-month, parallel-group, non-inferiority study to compare aesthetic restorations in primary anterior teeth in a paediatric dental clinic: study protocol for a randomised controlled trial.
Not available
S-EPMC11800219 | biostudies-literature
ProteomicsAge-related changes in the proteome and mitochondrial metabolism of rabbit adipose-derived stromal/stem cells
In this study, the proteome and metabolic properties of primary subcutaneous (s) and visceral (v) adipose tissue-derived stromal stem cells (ASC) from old and young rabbits were analysed by a mass spectrometry-based label-free quantification approach and combined with metabolic mitochondrial respira...
ORGANISM(S): Oryctolagus cuniculus (Rabbit) 
2025-01-19 | PXD057467 | Pride
Stem cell ageing Mitochondrial metabolism Rabbit Adipose-derived stromal stem cells 
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