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ProteomicsCardiac tissue remodeling as a new marker to predict cardiac dysfunction induced by radiotherapy.
The contribution of radiotherapy, per se, in late cardiotoxicity remains controversial. An experimental model was developed, in which rat hearts were exposed to a range of ionizing radiation doses, to clarify its impact on the development of early cardiac dysfunction. Rat’s hearts were exposed to da...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-09-08 | PXD033194 | Pride
Gls Cardiac tissue Cardiac muscle Cardiooncology Cardiac dysfunction Radiotherapy 
ProteomicsSubtherapeutic-Dose of Ionizing Radiation Reprograms the Pre-Metastatic Lung Niche, Accelerating Its Formation and Promoting Metastasis
Pre-metastatic niche (PMN) formation is a critical step in metastatic progression, yet the biological effect of subtherapeutic-dose of ionizing radiation (SDIR) following radiotherapy on this process remains unclear. Using a 4T1 breast cancer mouse model, we investigated the effects of SDIR (3×0.3 G...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-21 | PXD062108 | Pride
Pre-metastatic niche  subtherapeutic-dose of ionizing radiation  metastasis 
TranscriptomicsExpression data from Human Umbilical Vein Endothelial Cells (HUVECs) exposed to WT and V30M transthyretin (TTR)
The biological effects of TTR proteins in the vasculature remain unknown. We used microarrays to detail the modulation of gene expression on HUVECs by V30M TTR when compared to cells exposed to WT TTR. HUVECs (passage 7) were cultured in the presence of WT or V30M TTR at 4M-BM-5M for 3 hours. RNA wa...
ORGANISM(S): Homo sapiens 
2013-09-13 | E-GEOD-44856 | biostudies-arrayexpress
TranscriptomicsRNA-seq of leaf tissue from four genotypes of Lathyrus sativus infected with the Erysiphe pisi
Four L. sativus accessions, exhibiting varying levels of resistance to E. pisi (resistant, partially resistant, partially susceptible, and susceptible), were analysed using dual RNA-seq. Leaflets from each plant were sampled at 0 (non-inoculated), 6, 12, 24, 48, and 72 hours after inoculation. Forty...
ORGANISM(S): Lathyrus sativus 
2025-02-28 | E-MTAB-14647 | biostudies-arrayexpress
ProteomicsThe haemolymph proteome of Mytilus edulis: insights into the circulatory system and innate immunity of marine mussels
Mussels are a group of sessile and filter-feeding invertebrates, and are key structural elements of many marine and freshwater ecosystems. The mussel haemolymph is the first defense line to pathogen infection and inflammation with an innate immune response. Despite the importance of this body fluid ...
ORGANISM(S): Mytilus edulis (Blue mussel) 
2015-09-14 | PXD001951 | Pride
Innate immunity Shotgun proteomics Mytilus edulis Haemolymph Biomarker 
UnknownRhinovirus is an important pathogen in upper and lower respiratory tract infections in Mexican children.
Not available
S-EPMC4349319 | biostudies-literature
UnknownSARS-CoV-2 can recruit a heme metabolite to evade antibody immunity.
Not available
S-EPMC8163077 | biostudies-literature
UnknownSARS-CoV-2 recruits a haem metabolite to evade antibody immunity.
Not available
S-EPMC7852234 | biostudies-literature
UnknownNGFR induces melanoma invasion and immunotherapy resistance through myosin light chain 2 modulation
Not available
S-SCDT-10_1038-S44318-026-00803-2 | biostudies-other
UnknownHyperoxemia and excess oxygen use in early acute respiratory distress syndrome: insights from the LUNG SAFE study.
Not available
S-EPMC7110678 | biostudies-literature
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