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ProteomicsEvaluation of suitability of dried saliva spots for in-depth proteome analyses of clinical applications - Additional file
We performed a single-shot DIA-MS proteome analysis of dried saliva spots (DSS) to investigate whether it provides a platform to complement the dried blood spot (DBS) data.
ORGANISM(S): Homo Sapiens (human) 
2022-04-26 | PXD032116 | JPOST Repository
ProteomicsEvaluation of suitability of dried saliva spots for in-depth proteome analyses of clinical applications
We performed a single-shot DIA-MS proteome analysis of dried saliva spots (DSS) to investigate whether it provides a platform to complement the dried blood spot (DBS) data.
ORGANISM(S): Homo Sapiens (human) 
2022-04-26 | PXD031181 | JPOST Repository
ProteomicsIn-depth data independent acquisition-mass spectrometry proteomic analysis of juvenile dermatomyositis serum samples reveals protein expression changes associated with muscle-specific autoantibodies
We analyzed sera from five JDM patients, each with three MSAs (anti-melanoma differentiation-associated protein 5 antibodies; anti-MDA5, anti-nuclear matrix protein 2 antibodies; anti-NXP2, or anti-transcriptional intermediary factor 1 alpha and/or gamma subunits antibodies; anti-TIF-1γ) and five he...
ORGANISM(S): Homo Sapiens (human) 
2023-04-23 | PXD036960 | JPOST Repository
TranscriptomicsGene expression profiles in the liver of obese AIM+/+ and AIM-/- mice
To elucidate differential preventive roles of the blood apoptosis inhibitor of macrophage (AIM) protein in fat deposition and hepatocarcinoma development, we have performed microarray analysis to assess putative difference in expression of genes related to carcinnogenesis in the liver of AIM+/+ and...
ORGANISM(S): Mus musculus 
2015-12-23 | E-GEOD-53972 | biostudies-arrayexpress
TranscriptomicsGenes affected by PAD4 deficiency in LSK cells obtained from mouse bone marrow.
We found PAD4, which is one of the transcriptional co-regulator by histone modification, was highly expressed in lineage-, Sca-1+, c-kit+ (termed as LSK) cells of mouse bone marrow. To find the target genes which are regulated by PAD4 in LSK cells, we analyzed gene expression in PAD4-deficient mouse...
ORGANISM(S): Mus musculus 
2013-06-01 | E-GEOD-45482 | biostudies-arrayexpress
ProteomicsProteome analysis of brain vessels (the anterior cerebral artery and the middle cerebral artery) from 24-month-old candesartan-treated and nontreated Htra1 KO mice
CARASIL (cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy) is a hereditary cerebral small-vessel disease caused by loss of function mutations of HTRA1, which is a serine protease with a variety of targets, including extracellular matrix proteins. Htra1-KO m...
ORGANISM(S): Mus Musculus (mouse) 
2021-11-16 | PXD023477 | JPOST Repository
ProteomicsIn-depth proteome analysis of Hela cell culture conditioned media containing fetal bovine serum.
We performed DIA-MS based proteomic analysis of Hela cells conditioned media containing fetal bovine serum by albumin (Alb)-depletion and non-depletion. In addition, we attempted to enrich secreted proteins by reducing the volume of culture medium (10mL, 5mL and 2mL). The supernatants of each cultur...
ORGANISM(S): Homo Sapiens (human) 
2022-02-22 | PXD024272 | JPOST Repository
ProteomicssJIA serum proteome profiling with DIA-MS
We performed a DIA-MS proteomic analysis of sera from systemic juvenile idiopathic arthritis with different activity phases using a high protein depletion process. We profiled the proteins in the sera that differed significantly in their activity phase.
ORGANISM(S): Homo Sapiens (human) 
2022-04-26 | PXD030413 | JPOST Repository
ProteomicsUltra-fast proteome analysis of HEK293T cells using Q-Orbitrap MS
We established an ultrafast proteomic method based on a 5-min gradient LC and quadrupole-Orbitrap mass spectrometer.
ORGANISM(S): Homo Sapiens (human) 
2022-07-28 | PXD034227 | JPOST Repository
ProteomicsDeep proteome analysis by DIA-MS
To expand proteome coverage, the MS range in DIA-MS was examined. In addition, we analyzed host proteins in the feces of control and repeated social defeat stress (R-SDS) model mice by DIA-MS with an optimal MS range.
ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse) 
2022-04-28 | PXD032698 | JPOST Repository
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