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ProteomicsAqueous Proteomics of Recurrent Rhegmatogenous Retinal Detachment
The aqueous collected during primary surgery of 13 patients suf-fering RRD (RRD group) was compared to 11 age and sex-matched patients successfully operated for rhegmatogenous RD with no recurrency after 12-months follow-up (noRRD Group), regardless of surgical technique.
ORGANISM(S): Homo sapiens (Human) 
2026-06-01 | PXD070155 | Pride
Human Aqueous humor Hplc-ms 
ProteomicsExploring proteome perturbations by citicoline treament
This project deals with an investigation into perturbations of intracellular proteome of SH-SY5Y cells stimulated with two doses of citicoline (1 mM and 0.1 mM) for 6h and 18h in vitro. Citicoline is a nootropic agent used for the therapy of glaucoma, which is a neurodegenerative disorder characteri...
ORGANISM(S): Homo sapiens (Human) 
2026-02-02 | PXD061053 | Pride
Citicoline Glaucoma Proteostasis 
ProteomicsProteomics study of HDAC6 silenced cells
The proteomic analysis here introduced was set up and performed to figure out global perturbations of the proteome of a breast cancer human cell line in the presence/absence of HDAC6 silencing.
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD054378 | Pride
Shot-gun Hdac6 Mass spectrometry 
ProteomicsALTERED PATTERN OF PROTEOLYSIS OF EXTRACELLULAR PROTEINS IN RHEGMATOGENOUS RETINAL DETACHMENT BY MINING OF TRYPTIC AND N-TERMINI DATASETS FROM VITREOUS HUMOR PROTEOME
Retinal detachment is a severe eye condition characterized by the detachment of the neurosensory retina from the retinal pigment epithelium and caused by retinal tears. Pars plana vitrectomy is the elective surgical procedure during which vitreous humor, a fluid which shapes the eye globe and suppor...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PXD057155 | Pride
Eye Vitreous humor Uhplc-ms Ocular fluids Dda 
ProteomicsProfiling of the proteome of peripheral blood mononuclear cells of subjects diagnosed with primary open angle glaucoma
This study reports the first characterization of the intracellular proteome of peripheral blood mononuclear cells (PBMC) isolated from subjects diagnosed with primary open angle glaucoma (POAG)by shot-gun proteomics. Glaucoma is a chronic optic neuropathy and among the first causes of irreversible...
ORGANISM(S): Homo sapiens (Human) 
2025-09-22 | PXD059976 | Pride
Glaucoma Peripheral blood mononuclear cells Shot gun proteomics Immune system 
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