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ProteomicsAdverse Effects of Bisphenol A and its substitute compounds on human SGBS preadipocytes
Bisphenol A (BPA), which is used in a variety of consumer-related plastic products, was reported to cause metabolic disruption. Substitute compounds are increasingly emerging, but are not sufficiently investigated. In this study, we aimed to investigate the mode of action of BPA and four of its subs...
ORGANISM(S): Homo sapiens (Human) 
2021-08-05 | PXD023227 | Pride
Bpa Adipocytes Sgbs Human Bisphenol a 
ProteomicsTHP-1 cells treated with plasticizer DINCH and metabolite MINCH
Since 2008, the consumption of the plasticizer bis (2-ethylhexyl) phthalate (DEHP) in the manufacture of plastic products has been restricted due to several adverse health effects. 1,2-cyclohexanedicarboxylic acid diisononyl ester (DINCH) is increasingly used as a harmless substituent for DEHP. Howe...
ORGANISM(S): Homo sapiens (Human) 
2022-01-10 | PXD027744 | Pride
Endocrine disruption Plasticizers Minch Dinch 
ProteomicsEffects of plasticizers on adult human adipocytes (SGBS) using global proteomics
SGBS cells were used as a model system to investigate the cellular mode of action of a variety of plasticizers in human adipocytes. In brief, cells were cultured at 5% CO2 and 37°C in 95% humidity. Cells of generation 40 and passage 3 after thawing were grown to confluence with DMEM/F12 containing 3...
ORGANISM(S): Homo sapiens (Human) 
2022-06-20 | PXD030843 | Pride
Xenobiotics Tmt Adipocytes Global proteomics Untargeted proteomics Sgbs 
ProteomicsEffects of plasticizers on human preadipocytes (SGBS) using global proteomics
SGBS cells were used as a model system to investigate the cellular mode of action of a variety of plasticizers in human adipocytes. In brief, cells were cultured at 5% CO2 and 37°C in 95% humidity. Cells of generation 40 and passage 3 after thawing were grown to confluence with DMEM/F12 containing 3...
ORGANISM(S): Homo sapiens (Human) 
2022-06-20 | PXD031041 | Pride
Xenobiotics Endocrine disruption Adipocytes Tmt Sgbs Ppargamma 
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