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ProteomicsPlasmodium falciparum Chr3C7 and Chr3C16 DiQ-BioID data
As part of a larger study characterizing all unknown 'nonsecretory' proteins encoded on chromosome 3 of P. falciparum parasites, we selected two candidate proteins (Chr3C7 and Chr3C16) to obtain interactomes using dimerisation-induced quantitative BioID (DiQ-BioID). This set of experiments r...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2023-02-17 | PXD035332 | Pride
Chromosome-wide screen Malaria Subcellular localisation Mitosis Plasmodium falciparum 
UnknownThird-generation anti-CD19 CAR T cells for relapsed/refractory chronic lymphocytic leukemia: a phase 1/2 study.
Not available
S-EPMC11519001 | biostudies-literature
ProteomicsPlasmodium falciparum Kelch13, Eps15 and Clathrin HC interactomes obtained using a dimerisation-induced quantitative BioID (DiQ-BioID)
In order to identify Kelch13 interaction partners in living P. falciparum parasites, we established a new type of BioID we termed dimerisation-induced quantitative BioID (DiQ-BioID) that takes advantage of the FKBP-FRB heterodimerisation system. For DiQ-BioID the target is endogenously tagged with F...
ORGANISM(S): Plasmodium falciparum 
2021-12-02 | PXD008219 | Pride
Eps15 Dimerisation-induced quantitative bioid (diq-bioid) Plasmodium falciparum Artemisinin resistance Vesicle trafficking Kelch13 Clathrin hc 
TranscriptomicsMechanisms and rescue strategies of Calcineurin inhibitor mediated tolerance abrogation
To ensure safety tolerance induction protocols are accompanied by conventional immunosuppressive drugs IS. But IS such as calcineurin inhibitors CNI can interfere with tolerance induction. We investigated the effect of an additional CNI treatment on anti-CD4 mAb-induced tolerance induction upon rat ...
ORGANISM(S): Rattus norvegicus 
2013-09-01 | E-GEOD-40454 | biostudies-arrayexpress
ProteomicsRebuilding core abscisic acid signaling pathways of Arabidopsis in yeast
The signaling pathway of the phytohormone abscisic acid (ABA) regulates responses towards abiotic stress such as drought and high osmotic conditions. The multitude of functionally redundant components involved in ABA signaling, poses a major challenge for elucidating the largely unresolved response ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) Saccharomyces cerevisiae (Baker's yeast) 
2019-07-30 | PXD013669 | Pride
Arabidopsis Yeast Snrk2 phosphorylation Aba 
ProteomicsBrown adipocytes proteome upon acute adrenergic stimulation
Mice and other small mammals heavily rely on UCP1-mediated non-shivering thermogenesis in the cold, and thus the unexpected cold resistance of UCP1-knockout (UCP1KO) mice has always been and still is an unresolved mystery inextricably intertwined with alternative means of thermogenesis and futile su...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-25 | PXD025854 | Pride
Proteomics Brown adipocyte Mass spectrometry Proteome 
UnknownBacterial protein domains with a novel Ig-like fold bind human CEACAM receptors
Not available
S-SCDT-EMBOJ-2020-106103 | biostudies-other
ProteomicsCombinatorial high throughput drug screening identifies a synergistic drug interaction that sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade
KRAS-mutant pancreatic ductal adenocarcinoma (PDAC) is highly immunosuppressive and resistant to targeted therapies, immune checkpoint blockade and engineered T cells. Here, we performed a systematic high throughput combinatorial drug screen and identified a synergistic interaction between the MEK i...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-23 | PXD023267 | Pride
Pancreatic cancer Combination therapy Scrna-seq Immune checkpoint inhibition Kinobead pull-downs Lc-ms/ms 
ProteomicsBioID with P. falciparum protein PhiL1
The aim of the project was to identify proteins proximal to Plasmodium falciparum PhiL1
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2021-05-03 | PXD024237 | Pride
Lc-msms Plasmodium falciparum Phil1 
TranscriptomicsInhibition of dendritic cell maturation and effector function
The initiation of donor derived dendritic cell (DC) adhesion and migration are one of the key events mediated by ischemia reperfusion injury (IRI) following solid organ transplantation. Recently we have been able to demonstrate that a single donor treatment with the synthetic metalloporphyrin cobalt...
ORGANISM(S): Mus musculus 
2010-05-18 | E-GEOD-8452 | biostudies-arrayexpress
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