Sort   by:  
 Page size 
TranscriptomicsRNAi knock down of export factors in Drosphila Schneider cell lines
Six different endogenous Drosophila proteins (all potential export factors) have been inactivated using RNAi and leptomycin B (LMB) treatments. Five different endogenous Drosophila proteins (all potential export factors) have been targeted by RNAi. The effect on mRNA export is analyzed by monitoring...
ORGANISM(S): Drosophila melanogaster 
2003-05-15 | E-MEXP-4 | biostudies-arrayexpress
TranscriptomicsRNAi of Drosophila dTip60 in SL2 cells to investigate regulation of gene expression by the histone acetyltransferase dTip60
We used microarrays to detail the global gene expression changes following RNAi knock-down of dTip60 in Drosophila SL2 cells Experiment Overall Design: We compared SL2 cells treated with dTip60-RNAi with SL2 cells mock-treated with eGFP-RNAi to determine global gene expression changes by microarray ...
ORGANISM(S): Drosophila melanogaster 
2010-01-23 | E-GEOD-13878 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA on hemocytes from wandering larvae of Drosophila melanogaster not infested and infested by Leptopilina boulardi
We aimed at characterizing the diverse hemocyte populations present in the hemolymph of the Drosophila larvae. The hemocytes were collected from wandering larvae infested by wasp (WI) or not infested (NI). The hemocytes were then sequenced using 10x genomics technology.
ORGANISM(S): Drosophila melanogaster 
2020-03-12 | E-MTAB-8698 | biostudies-arrayexpress
TranscriptomicsRNAi knock down in Drosophila of THO2 and HPR1 proteins from S2 cells
THO2 and HPR1 proteins were co-depleted from Drosophila S2 cells and their role in mRNA export analysed by comparing total RNA and cytoplasmic RNA
ORGANISM(S): Drosophila melanogaster 
2005-01-01 | E-MEXP-88 | biostudies-arrayexpress
GenomicsMINCR is a MYC-induced lncRNA able to modulate MYC’s transcriptional network in Burkitt lymphoma cells
Despite the established role of the transcription factor MYC in cancer, little is known about the involvement of lncRNAs in mediating MYC’s function. Here we have intersected RNA-sequencing data from MYC-inducible cell lines, from a cohort of 91 mature B-cell lymphomas and from sorted germinal-cente...
EGAS00001001199 | EGA
ProteomicsProteomics approach to identify sample manipulation in forensic toxicology for hair and urine
Urine and hair are among the primary biological matrices used for drug and abstinence testing in clinical, forensic, and anti-doping settings. A persistent challenge in such analyses is the adulteration of samples: through dilution, substitution, or chemical modification, aimed at concealing the pre...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD064208 | Pride
Forensics Hair Urine Lc-ms Manipulation 
TranscriptomicsCDH1 knockout in mice
Employing Cre/loxP technology, a mouse model of liver specific Cdh1 (E-cadherin) depletion was created (fl/fl | +/wt). Previously, the mice had already been compared to littermates with normal Ecadherin levels (fl/fl | wt/wt), using a broad range of laboratory methods (Serum parameters, long-term we...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-54234 | biostudies-arrayexpress
TranscriptomicsA tRNA-derived microRNA modulates the DNA damage response and is downregulated in B cell lymphoma
Sequencing studies from several model systems have suggested that diverse and abundant small RNAs may derive from tRNA, but the function of these molecules remains undefined. Here we demonstrate that one such tRNA fragment, cloned from human B cells and designated CU1276, in fact possesses the func...
ORGANISM(S): Homo sapiens 
2012-12-19 | E-GEOD-42989 | biostudies-arrayexpress
Genomicsena-DATASET-DKFZ-IBIOS-16-07-2015-15:45:02:488-51 - samples
Despite the established role of the transcription factor MYC in cancer, little is known about the impact of a new class of transcriptional regulators, the long non-coding RNAs (lncRNAs), on the way MYC is able to influence cellular transcriptome. To this aim we have intersected RNA-sequencing data f...
EGAD00001001441 | EGA
TranscriptomicsExpression data from CD4-positive HTLV-positive cell lines and from CD4-positive HTLV-negative primary cells.
We used microarrays to compare the global programme of gene expression in HTLV-positive, ATL-derived and HTLV-positive in vitro-transformed cell lines with that of uninfected primary CD4 T cells. Cells were harvested one day after splitting, in case of primary T cells, cells were harvested after rea...
ORGANISM(S): Homo sapiens 
2009-08-20 | E-GEOD-17718 | biostudies-arrayexpress
Sort   by:  
 Page size