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ProteomicsDiverged Trypanosome MICOS as a Hub for Mitochondrial Cristae Shaping and Protein Import
The mitochondrial contact site and cristae organization system (MICOS) is a complex responsible for proper cristae formation. Empirical data about this ubiquitous complex is limited to opisthokont models (e.g. yeast), impeding understanding of its core properties and adaptation potential to diverse ...
ORGANISM(S): Trypanosoma brucei 
2018-09-13 | PXD009601 | Pride
Mitochondria  cristae  intermembrane space  micos  protein import  trypanosoma brucei  lc-ms/ms  label-free  tmt 
ProteomicsChemical cross-linking enables drafting ClpXP proximity maps and taking snapshots of in vivo interaction networks
Protein-protein interactions within complexes and networks are often dynamic and their elucidation remains a challenging task. Here, we show on the example of the proteolytic ClpXP complex the power of combined chemical cross-linking and mass-spectrometry to capture transient binding interactions wi...
ORGANISM(S): Homo sapiens (Human) Escherichia coli Staphylococcus aureus 
2018-11-21 | PXD009224 | Pride
Clpxp Interacting proteins Chemical cross-linking Co-ip Clpp 
UnknownVariants in SCAF4 Cause a Neurodevelopmental Disorder and Are Associated with Impaired mRNA Processing.
Not available
S-EPMC7477272 | biostudies-literature
ProteomicsChinese hamster ovary (CHO) cell Surfaceome LC-MSMS and mRNA expression analysis
The production of biopharmaceuticals relies on robust cell systems that can produce recombinant proteins at high levels, and grow and survive in the stressful bioprocess environment. Chinese hamster ovary cells (CHO) as the main production hosts offer a variety of advantages including robust growth ...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2022-10-15 | PXD033581 | Pride
Lc-msms Signaling pathways Mrna expression Cho cells Surfaceome 
UnknownRisk of Acute Liver Injury With Antiretroviral Therapy by Viral Hepatitis Status.
Not available
S-EPMC5407218 | biostudies-literature
UnknownEXCHANGE-2: investigating the efficacy of add-on plasma exchange as an adjunctive strategy against septic shock-a study protocol for a randomized, prospective, multicenter, open-label, controlled, parallel-group trial.
Not available
S-EPMC10105400 | biostudies-literature
UnknownSubcutaneous Apomorphine Infusion Initiation Is Associated with Impulse Control Disorder Attenuation in Advanced Parkinson's Disease Patients: Insights from the French NS-Park Cohort.
Not available
S-EPMC12839497 | biostudies-literature
UnknownClinical, neuroradiological and genetic findings in pontocerebellar hypoplasia.
Not available
S-EPMC9136852 | biostudies-literature
UnknownUpdated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference.
Not available
S-EPMC6174113 | biostudies-literature
UnknownCreation of forest edges has a global impact on forest vertebrates.
Not available
S-EPMC5681864 | biostudies-literature
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