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TranscriptomicsChromatin immunoprecipitation of Drosophila Schneider cells using antibodies against HP1a
Preparation of nuclear extracts

D. melanogaster Schneider cells were prepared as previously described by Andrews and Faller (1991). Briefly, in a typical preparation, 8x106 cells (grown in Schneider medium plus 10% fetal calf serum; GIBCO-BRL) were pelleted and resuspended in 1,5 mL cold PBS1...
ORGANISM(S): Drosophila melanogaster 
2009-10-12 | E-MEXP-1556 | biostudies-arrayexpress
GenomicsDefining the influence of the A12 subunit on transcription elongation and termination by rna polymerase I
Defining the influence of the A12 subunit on transcription elongation and termination by rna polymerase I
PRJNA597054 | ENA
TranscriptomicsTranscription profiling of CACNA1E overexpression in human embryonic kidney HEK293 cells to investigate the involvement of CACNA1E in Wilms tumorigenesis
Wilms tumour (nephroblastoma) is the most common paediatric renal tumour, affecting 1 in 10,000 children. Despite the excellent survival of patients treated with a combination of surgery, chemotherapy and radiotherapy, approximately 15% will relapse and die of this disease. We have identified CACNA1...
ORGANISM(S): Homo sapiens 
2006-12-01 | E-MEXP-587 | biostudies-arrayexpress
GenomicsChIP-Seq of fly Schneider S2 cells to investigate CID islands
The centromere-specific Histone H3-variant CENH3 (also known as CENP-A) is considered to be an epigenetic mark for establishment and propagation of centromere identity. Pulse-induction of CENH3 (Drosophila CID) in Schneider S2 cells incorporates into noncentromeric regions and generates CID islands ...
ORGANISM(S): Drosophila melanogaster 
2011-07-15 | E-MTAB-652 | biostudies-arrayexpress
ModelsSchneider2006_CardiacContractionModel
This a model from the article: Mechanism of the Frank-Starling law--a simulation study with a novel cardiac muscle contraction model that includes titin and troponin I. Schneider NS, Shimayoshi T, Amano A, Matsuda T. J Mol Cell Cardiol. 2006;41(3):522-...
2005-01-01 | MODEL7907879432 | BioModels
TranscriptomicsCaM Kinase II mediates maladaptive post-infarct remodeling but not acute myocardial ischemia/reperfusion injury
Calcium/calmodulin-dependent protein kinase II (CaMKII) was suggested to mediate ischemic myocardial injury and adverse cardiac remodeling. However, the specific functions of the CaMKII isoforms and splice variants in ischemia/reperfusion (I/R) injury have not been investigated yet. Thus, we studied...
ORGANISM(S): Mus musculus 
2014-09-08 | E-GEOD-58486 | biostudies-arrayexpress
TranscriptomicsRNAi knock down of export factors in Drosphila Schneider cell lines
Six different endogenous Drosophila proteins (all potential export factors) have been inactivated using RNAi and leptomycin B (LMB) treatments. Five different endogenous Drosophila proteins (all potential export factors) have been targeted by RNAi. The effect on mRNA export is analyzed by monitoring...
ORGANISM(S): Drosophila melanogaster 
2003-05-15 | E-MEXP-4 | biostudies-arrayexpress
TranscriptomicsPreprocessed reduced representation bisulfite sequencing (RRBS) data from 173 human umbilical cord blood samples, collected for a study on associations between perinatal DNA methylation marks and progression to type 1 diabetes by age 15
The samples were collected from the participants of the Finnish Diabetes Prediction and Prevention (DIPP) Study, born between 1995 and 2006. DIPP is a prospective follow-up cohort of children with a moderate or high risk of type 1 diabetes, based on the HLA-DR-DQ genotype. Islet cell autoantibodies ...
ORGANISM(S): Homo sapiens 
2022-06-06 | E-MTAB-10530 | biostudies-arrayexpress
UnknownProSAP1 and membrane nanodomain-associated syndapin I promote postsynapse formation and function.
Not available
S-EPMC4003247 | biostudies-literature
ProteomicsHLA class I-naturally presented synovial tissue peptides are recognized by CD8+ T lymphocytes from rheumatoid arthritis patients
Introduction: Rheumatoid arthritis (RA) is an autoimmune disease resulting from a response driven by self-reactive CD4+ T cells that recognize autoantigenic peptides presented by antigen-presenting cells (APCs). Recent evidence suggests that CD8+ T cells are also important players in this process. T...
ORGANISM(S): Homo sapiens (Human) 
2026-08-27 | PXD079646 | Pride
Cd8+ t cells Hla class i Rheumatoid arthritis Autoantigens Immunopeptidomics 
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