Autoantigens - OmicsDI

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A proteomics workflow reveals predictive autoantigens in idiopathic pulmonary fibrosis (cohort 2)

Rationale: The diagnosis of idiopathic pulmonary fibrosis (IPF) requires exclusion of an underlying autoimmune disease, as present in interstitial lung diseases associated with connective tissue diseases (CTD-ILD). The prevalence of autoantibodies in IPF patients is currently unknown. Objectives: An...

ORGANISM(S): Homo sapiens (Human)

2021-02-22 | PXD024123 | Pride

A proteomics workflow reveals predictive autoantigens in idiopathic pulmonary fibrosis (cohort 1)

ORGANISM(S): Homo sapiens (Human)

2021-02-22 | PXD024113 | Pride

Ipf Ctd-ild Clinical proteomics Autoantibodies Autoimmunity Lung fibrosis

Immunoprecipitated proteins using serum pools of patients with juvenile idiopathic arthritis

Different exploratory methods were used in search for autoantigens that can predict outcome of disease. Plasma pools from patient with and without uveitis were used for immunoprecipitation to filter out autoantigens that was then further analyzed in targeted arrays.

ORGANISM(S): Homo sapiens (Human)

2023-01-05 | PXD038570 | Pride

Juvenile idiopathic arthritis Antibody profiling Autoantibodies Autoantigens Immunoprecipitation

Granzyme B cleavage of autoantigens in autoimmunity.

Not available

S-EPMC3136751 | biostudies-literature

Improved approach to identify cancer-associated autoantigens.

Not available

S-EPMC5604223 | biostudies-literature

Islet autoantigens: structure, function, localization, and regulation.

Not available

S-EPMC3405822 | biostudies-literature