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ProteomicsA translational protocol for the analysis of plasma-derived extracellular vesicle proteomics
We establish here an EV purification and proteomic analysis workflow in a real world clinical setting in which we evaluate different variables, from blood collection through protein preparation for mass spectrometry (MS). We compare blood collection tubes, sample transportation and storage condition...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD058373 | Pride
Protocol Proteomics Preanalytics Liquid biopsy Plasma Extracellular vesicles Translation 
ProteomicsMicrobial functionality as affected by experimental warming of a temperate mountain forest soil - a metaproteomics survey
Soils are a huge reservoir of organic C, and the efflux of CO2 from soils is one of the largest fluxes in the global C cycle. Out of all natural environments, soils probably contain the greatest microbial biomass and diversity, which classifies them as one of the most challenging habitats for microb...
ORGANISM(S): uncultured soil microorganism 
2022-03-14 | PXD004428 | Pride
Soil microbial diversity Microbial community functionality Soil warming 
UnknownhnRNP R negatively regulates transcription by modulating the association of P-TEFb with 7SK and BRD4
Not available
S-SCDT-EMBOR-2022-55432-T | biostudies-other
TranscriptomicsStem cell factor Sox2 regulates the tumorigenic potential in human gastric cancer cells
Gastric cancer is still one of the most common causes of cancer-related death worldwide, which is mainly attributable to late diagnosis and poor treatment options. Infection with H. pylori, different environmental factors and genetic alterations are known to influence the risk of developing gastric ...
ORGANISM(S): Homo sapiens 
2013-12-31 | E-GEOD-42937 | biostudies-arrayexpress
ProteomicsPlatelet-phenotypes in chronic inflammation
In addition to their well-established role in thrombosis and hemostasis, there is growing evidence that platelets play a central role in systemic inflammatory processes. Therefore, we aimed to gain insights into the phenotype and possible platelet-subgroups in the context of different types of infla...
ORGANISM(S): Homo sapiens (Human) 
2025-10-08 | PXD057615 | Pride
Type 2 inflammation Platelets Psoriasis Type 3 inflammation Atopic dermatitis 
ProteomicsTarget Landscape of Clinical Kinase Inhibitors
Here, we provide a comprehensive overview of the selectivity profiles of 242 kinase inhibitors currently in clinical trials. We screened available inhibitors against human protein kinases by using the Kinobead technology resulting in a drug matrix identifying the druggable kinome and related protein...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-01-12 | MSV000081932 | MassIVE
UnknownPerformance evaluation of automated white matter hyperintensity segmentation algorithms in a multicenter cohort on cognitive impairment and dementia.
Not available
S-EPMC9877422 | biostudies-literature
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