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ProteomicsTemporal Changes in the Chlamydomonas Proteome in Response to High Light
Quantitative proteomic analysis of Chlamydomonas reinhardtii exposed to high light. Samples were taken 0h, 1h, 4h and 24h after beginning of the treatment.
ORGANISM(S): Chlamydomonas reinhardtii 
2019-04-23 | PXD010160 | Pride
Algae High light Q exactive plus Label-free quantification Chlamydomonas 
ProteomicsIntensity-based absolute quantification (iBAQ) of components of photosystem I monomers and dimers.
Photosystem I (PSI) enables photo-electron transfer and regulates photosynthesis in the bioenergetic membranes of cyanobacteria and chloroplasts. Being a multi-subunit complex, its macromolecular organization affects the dynamics of photosynthetic membranes. Here we reveal a chloroplast PSI from the...
ORGANISM(S): Chlamydomonas reinhardtii 
2023-03-11 | PXD026990 | Pride
Photosystem i Psi Ibaq Chlamydomonas reinhardtii 
ProteomicsChemical crosslinking of photosystem I antenna proteins
Chemical crosslinking (DSS) of proteins in conjunction with mass spectrometry was performed to identify protein-protein interactions between the light-harvesting proteins of PSI and PSII.
ORGANISM(S): Chlamydomonas reinhardtii 
2025-04-29 | PXD051493 | Pride
Photosynthesis Lhc Chlamydomonas Light harvesting 
ProteomicsIdentification of photosystem I components from Chlamydomonas reinhardtii grown under oxic and anoxic conditions
Photosystem I (PSI) enables photo-electron transfer and regulates photosynthesis in the bioenergetic membranes of cyanobacteria and chloroplasts. Being a multi-subunit complex, its macromolecular organization affects the dynamics of photosynthetic membranes. Here we reveal a chloroplast PSI from the...
ORGANISM(S): Chlamydomonas reinhardtii 
2023-03-11 | PXD027067 | Pride
Photosystem i Anoxia Blue native page Psi Chlamydomonas reinhardtii 
ProteomicsChronically elevated exogenous glucose elicits antipodal effects on the proteome signature of differentiating human pancreatic progenitors
The past decade revealed that cell identity changes, such as dedifferentiation or transdifferentiation, accompany the insulin-producing β-cell decay in most diabetes conditions. Mapping and controlling the mechanisms governing these processes is thus extremely valuable for managing the disease progr...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD022177 | Pride
Human Ipscs Glucose 
ProteomicsIn vivo hyperglycemia exposure elicits distinct period-dependent effects on human pancreatic progenitor differentiation, conveyed by oxidative stress
Objective: The loss of insulin-secreting β-cells, ultimately characterizing most diabetes forms, demands the development of cell replacement therapies. The common endpoint for all ex vivo strategies is transplantation into diabetic patients. However, the effects of hyperglycemia environment on the t...
ORGANISM(S): Homo sapiens (Human) 
2020-02-12 | PXD015071 | Pride
Human induced pluripotent stem cells Hyperglycemia Oxidative stress Lc-ms/ms 
Proteomicsin vivo environment swiftly restricts human pancreatic progenitors towards monohormonal identity via a HNF1A/HNF4A mechanism
Generating insulin-producing β-cells from human induced pluripotent stem cells is a promising cell replacement therapy aimed at improving or curing certain forms of diabetes. Nevertheless, despite important recent advances, the efficient production of functionally mature β-cells is yet to be achieve...
ORGANISM(S): Homo sapiens (Human) 
2020-02-12 | PXD015955 | Pride
Human Ipsc Alginate In vivo transplant 
UnknownGenome-wide analysis identifies novel susceptibility loci for myocardial infarction.
Not available
S-EPMC7936531 | biostudies-literature
UnknownGenome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
Not available
S-EPMC3445021 | biostudies-literature
UnknownStudy of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
Not available
S-EPMC5974083 | biostudies-literature
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