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ProteomicsComplement profiling on sural nerves of patients with chronic inflammatory demyelinating polyneuropathy
Overall, 55 sural nerve biopsies from patients with CIDP (n=36) and CIDP-variants (n=18) were included into the study. Immunohistochemical analysis of the sural nerve specimens showed an aberrant deposition of terminal complement complex C5b-9 on endoneural capillaries in 52 (94%) of patients in add...
ORGANISM(S): Homo sapiens (Human) 
2025-09-29 | PXD056286 | Pride
Proteomics Gene expression Chronic inflammatory demyelinating polyneuropathy  complement profiles  sural nerve 
UnknownSeverity of Schistosoma haematobium co-infection with malaria in school-children is potentially modulated by host CD14 gene variants.
Not available
S-EPMC10486024 | biostudies-literature
UnknownComplement profiling of sural nerves in chronic-inflammatory demyelinating polyneuropathy.
Not available
S-EPMC12449320 | biostudies-literature
UnknownCell-mediated cytotoxicity within CSF and brain parenchyma in spinal muscular atrophy unaltered by nusinersen treatment.
Not available
S-EPMC11096380 | biostudies-literature
MetabolomicsThe patatin-like protein PlpD forms novel structurally dynamic homodimers in the Pseudomonas aeruginosa outer membrane

Members of the Omp85 superfamily of outer membrane proteins (OMPs) found in Gram-negative bacteria, mitochondria and chloroplasts are characterized by a distinctive 16-stranded β-barrel transmembrane domain and at least one periplasmic POTRA domain. All previously studied Omp85 proteins promote c...

2025-12-08 | MTBLS9803 | MetaboLights
ProteomicsProteomic analysis of cisplatin exposure on the kidney cortex proteome and the effect of preconditioning
Acute kidney injury and nephrotoxicity are important clinical side effects of cisplatin. Thus, the mechanisms of this disease, and potential treatment options are important to understand in their entity. Here, we analyzed the proteome of cisplatin induced acute kidney injury in a mouse model. Functi...
ORGANISM(S): Mus musculus (Mouse) 
2020-01-30 | PXD005525 | Pride
Caloric restriction Cisplatin Kidney 
ProteomicsInvestigation of GPCR-G protein coupling by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) : the GPBAR1 case.
G protein-coupled receptors (GPCRs) are key classes of proteins for drug discovery research as many of them are still orphans and their function poorly known. Their activation mechanism is roughly divided in two states : active and unactive states however related dynamics to switch from one state to...
ORGANISM(S): Homo sapiens (Human) 
2025-09-08 | PXD047827 | Pride
Cryo-em Gpbar1 G protein Gpcr-g protein Tgr5 Hdx-ms Gpcr 
UnknownDeterministic programming of human pluripotent stem cells into microglia facilitates studying their role in health and disease.
Not available
S-EPMC9618131 | biostudies-literature
ProteomicsC21, human microglial cell proteome
This project describes the proteome of a microglial cell line generated by differentiation of human SC.
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD024649 | Pride
Human Microglia 
UnknownCerebellar and subcortical atrophy contribute to psychiatric symptoms in frontotemporal dementia.
Not available
S-EPMC10089095 | biostudies-literature
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