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The NuA4 histone acetyltransferase (HAT) complex is required for gene specific regulation, cell cycle progression, and DNA repair. Dissection of the 13-subunit complex reveals that the Eaf7 subunit bridges Eaf5 with Eaf3, a H3K36me3-binding chromodomain protein, and this Eaf5/7/3 trimer is anchored ...
ORGANISM(S): Saccharomyces cerevisiae 
Secreted proteins found in the supernatant of different mutants were analyzed by mass spectrometry employing In source-CID. After analysis of intact N-glycopeptides on MS1 level, N-glycan compositions found were compared between two strains, consequently unraveling the molecular function of enzymes ...
ORGANISM(S): Chlamydomonas reinhardtii 
2019-11-19 | PXD012107 | Pride
Bronchopulmonary dysplasia (BPD) is the most common complication of prematurity and is characterized by impaired alveolar and vascular development. The aim of the study was to identify early BPD-relevant pathways by applying whole genome transcriptional profiling combined with protein measurements f...
Codelink Human Whole Genome from Blood taken at 72 hours after birht
Codelink Human Whole Genome from Blood taken at 72 hours after birht
Linker histone H1 and heterochromatin protein 1 (HP1) are essential components ofheterochromatin which contribute to the transcriptional repression of genes. It has been shown that the methylation mark on the histone H1 serves as a specific recognition code for the chromodomain of HP1, however, the ...
ORGANISM(S): Caenorhabditis elegans 
The BRIDGE-BPD study aims to discover new causal genes for Bleeding and Platelet Disorders (BPD) by high throughput sequencing using cluster analyses based on improved and standardized deep phenotyping of cases. BPD is one of the 13 Rare Disease projects under the NIHR BioResource Rare Diseases BRID...
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