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TranscriptomicsCharacterization of perivascular MSC from the adult human brain
Brain perivascular cells have been recently identified as new mesodermal cell type of the human brain. These cells reside in the perivascular niche and were shown to have mesodermal and – to a lesser extend – tissue-specific differentiation potential. Mesenchymal stem cells (MSCs) are widely dis...
ORGANISM(S): Homo sapiens 
2015-11-03 | E-GEOD-62505 | biostudies-arrayexpress
ProteomicsHmgb2 improves astrocyte to neuron conversion by Neurog2-dependent increase in accessibility of genes related to neuronal maturation
Direct conversion of reactive glial cells to neurons is promising avenue for the replacement therapies after brain injury or neurodegeneration. The overexpression of developmental neurogenic fate determinants in glial cells converts them to neurons. For the repair purposes the conversion is confined...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-06 | PXD044288 | Pride
Lc-msms Astrocytes Mouse 
ProteomicsDNMT and HDAC inhibition induces immunogenic neoantigens from human endogenous retroviral element-derived transcripts
Immunotherapies targeting cancer-specific neoantigens have revolutionized the treatment of cancer patients. Recent evidence suggests that epigenetic therapies synergize with immunotherapies, mediated bythe de-repression of endogenous retroviral element (ERV)-encoded promoters, and the initiation of ...
ORGANISM(S): Homo sapiens (Human) 
2023-08-18 | PXD035750 | Pride
Decitabine Ltr Cancer Erv Mhc Neoantigen Dnmt Hla Hdac Sb939 Immunopeptidomics Humna Immunotherapy 
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