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TranscriptomicsTranscription profiling of human B lymphocytes from Scott syndrome patient and daughter, treated with the A23187 calcium ionophore
B lymphoblast samples from control individual, Scott syndrome patient and Scott syndrome daughter. From each samples one part was treated with A23187 ca2+ ionophore. Treated and non-treated samples were then cultured further. Each sample was then processed in duplicate for hybridization on the micro...
ORGANISM(S): Homo sapiens 
2007-07-19 | E-GEOD-1028 | biostudies-arrayexpress
TranscriptomicsScott B cell studies
B lymphoblast samples from control individual, Scott syndrome patient and Scott syndrome daughter. From each samples one part was treated with A23187 ca2+ ionophore. Treated and non-treated samples were then cultured further. Each sample was then processed in duplicate for hybridization on the micro...
ORGANISM(S): Homo sapiens 
2004-03-05 | GSE1028 | GEO
TranscriptomicsHDAC3 modulates enhancer activity to regulate terminal B cell differentiation
B220+GL7+ (GC) and B220+GL7- (non-GC) B cells were sorted from SRBC-immunized mice deficient for Hdac3 and wild type controls. RNA-sequencing revealed an upregulation of critical regulators of B cell differentiation in Hdac3-deleted animals. 10 days post-immunization with SRBCs, GC and non-GC B cell...
ORGANISM(S): Mus musculus 
2016-09-02 | E-GEOD-77113 | biostudies-arrayexpress
GenomicsHomo sapiens
Scott B cell studies
PRJNA87097 | ENA
ProteomicsProteomic analysis of B. cenocepacia H111 delta pglL strains
LFQ analysis of B. cenocepacia strain H111 strains to assess the impact of the loss of pglL (I35_RS13570)
ORGANISM(S): Burkholderia cenocepacia H111 
2021-07-21 | PXD023755 | Pride
Bacterial proteome Lfq Burkholderia 
ProteomicsAurora B opposes PP1 function in mitosis through phosphorylation of the conserved RVxF binding motif in PP1 regulatory proteins
Protein phosphatase 1 (PP1) is a highly conserved protein phosphatase that opposes the actions of a diverse set of Ser-Thr protein kinases by controlling the majority of serine-threonine (Ser-Thr) dephosphorylation reactions in eukaryotes. PP1 gains substrate specificity through binding to a large n...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-03-30 | MSV000082226 | MassIVE
TranscriptomicsTime Course Gene Expression Microarray Analysis of a Mouse B-cell Line (CH12.LX) Activated with Lipopolysaccharide and Treated with 2,3,7,8-Tetrachlorodibenzo-p-dioxin
The objective of the study was to characterize gene expression cascade involved in the suppression of B-cell activation and differentiation by 2,3,7,8-tetrachlorodibenzo-p-dixoxin (TCDD). The underlying hypothesis was that multiple nodes in the B-cell differentiation network are directly or indirect...
ORGANISM(S): Mus musculus 
2010-10-21 | E-GEOD-21272 | biostudies-arrayexpress
GenomicsLarge-scale viral genome analysis identifies novel clinical associations between hepatitis B virus and chronically infected patients
Despite the high global prevalence of chronic hepatitis B (CHB) infection, datasets covering the whole hepatitis B viral genome from large patient cohorts are lacking, greatly limiting our understanding of the viral genetic factors involved in this deadly disease. We performed deep sequencing of vir...
EGAS00001003689 | EGA
TranscriptomicsDNA methylation profiling in primary Diffuse Large B cell Lymphoma (DLBCL) and normal Germinal Center B Cells
Diffuse Large B-Cell Lymphoma (DLBCL) is the most common aggressive form of non-Hodgkin lymphoma with variable biology and clinical behavior. The current classification does not fully explain the biological and clinical heterogeneity of DLBCLs. In this study we carried out genome-wide DNA methylatio...
ORGANISM(S): Homo sapiens 
2014-01-18 | E-GEOD-54200 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression profile in RAG2+ B lineage cells from the small intestinal lamina propria and RAG2+ B lineage cells from the bone marrow
We used a RAG2-GFP reporter mouse to show that RAG+ B lineage cells can be found in the small intestinal lamina proria in normally-housed mice at weaning age. We used microarry expression analysis to compare the RAG2+ population in the gut to the RAG2+ B lineage population in the bone marrow. Microa...
ORGANISM(S): Mus musculus 
2013-07-12 | E-GEOD-48805 | biostudies-arrayexpress
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