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TranscriptomicsInduced inflammation perturbs testis formation in zebrafish
Effect of heat-killed E. coli on zebrafish sex determination.
ORGANISM(S): Danio rerio 
2012-06-08 | E-MEXP-3249 | biostudies-arrayexpress
UnknownDoes aggressive surgery improve outcomes? Interaction between preoperative disease burden and complex surgery in patients with advanced-stage ovarian cancer: an analysis of GOG 182.
Not available
S-EPMC4348639 | biostudies-literature
ProteomicsCarbene Footprinting Accurately Maps Binding Sites in Protein-Ligand and Protein-Protein Interactions
Specific interactions between proteins and their binding partners are fundamental to life processes. Differential protein footprinting using a new and efficient, photo-activated aryltrifluromethylcarbene probe together with mass spectrometry has been employed to identify protein-ligand and protein-p...
ORGANISM(S): Homo sapiens (Human) Gallus gallus (Chicken) 
2016-12-19 | PXD004971 | Pride
Lysozyme Carbene footprinting Usp5 Covalent labelling 
TranscriptomicsTranscription profiling of human prostate cancer between african-american and european-american men
The incidence and mortality rates of prostate cancer are significantly higher in African-American men when compared to European-American men. We tested the hypothesis that differences in tumor biology contribute to this survival health disparity. Using microarray technology, we obtained gene express...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6956 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Dnmt3L+/- sires compared to offspring of Dnmt3L+/+ sires to investigate the effect of paternal haploinsufficiency for Dnmt3L
There is increasing evidence that epigenetic information can be inherited across generations in mammals, despite extensive reprogramming both in the gametes and the early developing embryo. One corollary to this is that disruption of the establishment of epigenetic state in the gametes of a parent, ...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7384 | biostudies-arrayexpress
TranscriptomicsLoss of nuclear TDP-43 in ALS causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurons [fibroblasts]
Aims: Loss of nuclear TDP-43 characterises sporadic and most familial forms of amyotrophic lateral sclerosis (ALS). TDP-43 (encoded by TARDBP) has multiple roles in RNA processing. We aimed to determine whether 1) RNA splicing dysregulation is present in lower motor neurons in ALS and in a motor neu...
ORGANISM(S): Homo sapiens 
2014-06-01 | E-GEOD-33855 | biostudies-arrayexpress
ProteomicsMus musculus brown adipose tissue histone proteoforms
Histones were isolated from brown adipose tissue and liver from mice housed at 28, 22, or 8 C. Quantitative top- or middle-down approaches were used to quantitate histone H4 and H3.2 proteoforms. See published article for complimentary RNA-seq and RRBS datasets.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-06-05 | MSV000092105 | MassIVE
GenomicsGenome Landscape of Primary Pancreatic Ductal Adenocarcinoma
The purpose of the Australian ICGC Pancreatic Cancer Genome Sequencing Initiative study is to identify the common driving mutations underlying the initiation and development of Pancreatic Adenocarcinoma in a large cohort of pancreatic cancer patients (n=350). Matched genome sequences will be generat...
EGAS00001000154 | EGA
GenomicsABO_OICR_DATASET - samples
OICR PANCREATIC CANCER DATASET
EGAD00001000262 | EGA
GenomicsABO_OICR_DATASET_2 - samples
OICR PANCREATIC CANCER DATASET 2
EGAD00001000276 | EGA
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