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ProteomicsBRAF complexes - Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition
BRAF interactomes dependent on the mutation V600E are analyzed by SEC-PCP-SILAC and HA-IPs comparing V600E to WT
ORGANISM(S): Homo sapiens (Human) 
2017-01-03 | PXD004585 | Pride
Ap-ms V600e Sec-pcp-silac Caco2 cells Braf Lc-ms/ms 
ProteomicsGlobal interactome mapping reveals pro-cancerous interactions of NF-κB in breast cancer
NF-κB has an essential role in innate immune response and inflammation and is involved in cancer development and progression. We apply the SEC-PCP-SILAC method incorporating metabolic labeling, size exclusion chromatography and protein correlation profiling to construct a complex network of interact...
ORGANISM(S): Homo sapiens (Human) 
2024-02-28 | PXD040125 | Pride
Nf-κb Rela Breast cancer Protein correlation profiling Protein complexes Interaction Proteomics 
ProteomicsDynamic rewiring of the human interactome by interferon signalling
The type I interferon (IFN) response protects cells against viral pathogens by inducing the transcription of hundreds of IFN-stimulated genes (ISGs). Transcriptomic and biochemical approaches have established comprehensive catalogues of ISGs across species and cell types, but their antiviral mechani...
ORGANISM(S): Homo sapiens (Human) 
2020-05-15 | PXD013809 | Pride
Innate immunity Protein correlation profiling Proteomics Protein complexes Interferon stimulated gene Interferon Interactome 
UnknownProfiling the Escherichia coli membrane protein interactome captured in Peptidisc libraries.
Not available
S-EPMC6697469 | biostudies-literature
UnknownDiscrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition.
Not available
S-EPMC5331759 | biostudies-literature
ProteomicsYeast Proteomics
Proteomic study in Saccharomyces cerevisiae and Saccharomyces uvarum
ORGANISM(S): Saccharomyces uvarum Saccharomyces cerevisiae (Baker's yeast) 
2021-09-08 | PXD010136 | Pride
Saccharomyces uvarum Saccharomyces cerevisiae Pcp-silac Yeast Sec Lcmsms 
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