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ProteomicsLSD1 complexes - Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation
PCP-SILAC analysis of LSD1 protein complexes isolated from LNCaP cells
ORGANISM(S): Homo sapiens (Human) 
2016-01-11 | PXD003262 | Pride
Lc-ms/ms Prostate adenocarcinoma Lncap cells Pcp-silac 
ProteomicsBRAF complexes - Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition
BRAF interactomes dependent on the mutation V600E are analyzed by SEC-PCP-SILAC and HA-IPs comparing V600E to WT
ORGANISM(S): Homo sapiens (Human) 
2017-01-03 | PXD004585 | Pride
Ap-ms V600e Sec-pcp-silac Caco2 cells Braf Lc-ms/ms 
ProteomicsGlobal interactome mapping reveals pro-cancerous interactions of NF-κB in breast cancer
NF-κB has an essential role in innate immune response and inflammation and is involved in cancer development and progression. We apply the SEC-PCP-SILAC method incorporating metabolic labeling, size exclusion chromatography and protein correlation profiling to construct a complex network of interact...
ORGANISM(S): Homo sapiens (Human) 
2024-02-28 | PXD040125 | Pride
Nf-κb Rela Breast cancer Protein correlation profiling Protein complexes Interaction Proteomics 
ProteomicsDynamic rewiring of the human interactome by interferon signalling
The type I interferon (IFN) response protects cells against viral pathogens by inducing the transcription of hundreds of IFN-stimulated genes (ISGs). Transcriptomic and biochemical approaches have established comprehensive catalogues of ISGs across species and cell types, but their antiviral mechani...
ORGANISM(S): Homo sapiens (Human) 
2020-05-15 | PXD013809 | Pride
Innate immunity Protein correlation profiling Proteomics Protein complexes Interferon stimulated gene Interferon Interactome 
ProteomicsPCP SILAC of apoptosis initiation
Protein correlation profiling using size exclusion and blue native page analysis of protein complexes coupled with SILAC to enable the comparsion between conditions
ORGANISM(S): Homo sapiens (Human) 
2017-01-17 | PXD002892 | Pride
Human Apoptosis Jurkat Lc-ms 
UnknownA rapid and accurate approach for prediction of interactomes from co-elution data (PrInCE).
Not available
S-EPMC5654062 | biostudies-literature
UnknownProfiling the Escherichia coli membrane protein interactome captured in Peptidisc libraries.
Not available
S-EPMC6697469 | biostudies-literature
UnknownNovel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
Not available
S-EPMC3102290 | biostudies-literature
UnknownDiscrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition.
Not available
S-EPMC5331759 | biostudies-literature
ProteomicsProtein correlation of Mus musculus tissues
SILAC based protein correlation profiling using size exclusion of protein complexes derived from seven Mus musculus tissues (Heart, Brain, Liver, Lung, Kidney, Skeletal Muscle, Thymus)
ORGANISM(S): Mus musculus (Mouse) 
2018-04-24 | PXD007288 | Pride
Interactomes Silac Pcp Interactions 
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